{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T13:03:13Z","timestamp":1781701393532,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T00:00:00Z","timestamp":1685318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T00:00:00Z","timestamp":1685318400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to devise a simple assessment system for bone metastases (BMs) from lung cancer (LC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 368 LC patients with BMs who underwent radiotherapy (RT) were retrospectively reviewed. Prognostic factors were evaluated using multivariate analysis, and a scoring system based on regression coefficients was devised.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median follow\u2010up time for survival was 4.3\u2009months, and the 0.5\u2010year overall survival (OS) rate was 44.7%. In the multivariate analysis, the significant prognostic factors were performance status (PS), metastases to internal organs, and post\u2010RT molecular\u2010targeting therapies (MTs) (tyrosine kinase inhibitors, and\/or immune checkpoint inhibitors). A scoring system aggregating points assigned to each risk factor was created (2 points; non\u2010administration of post\u2010RT MTs, 1 point; PS\u2009\u22653 and metastases to internal organs). The median OSs were 25.0\u2009months, 12.8\u2009months, and 2.5\u2009months in patients with a total score of 0 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200922), 1\u20132 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009124), and 3\u20134 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009221), respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This easy\u2010to\u2010use scoring system is useful for selecting patients who received comparatively high\u2010dose fractionated RT for BMs from LC. Updates are required to follow the progress of systemic therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.14903","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T01:09:10Z","timestamp":1685408950000},"page":"1795-1801","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["An easy tool to predict survival in patients with bone metastatic lung cancer treated with palliative radiotherapy"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2219-6708","authenticated-orcid":false,"given":"Kenji","family":"Makita","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology National Hospital Organization Shikoku Cancer Center  Matsuyama Japan"},{"name":"Department of Radiology Ehime University Graduate School of Medicine  Toon Japan"},{"name":"Department of Radiology Ehime Prefectural Central Hospital  Matsuyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Hamamoto","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology National Hospital Organization Shikoku Cancer Center  Matsuyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromitsu","family":"Kanzaki","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology National Hospital Organization Shikoku Cancer Center  Matsuyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Nagasaki","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology National Hospital Organization Shikoku Cancer Center  Matsuyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Kozuki","sequence":"additional","affiliation":[{"name":"Department of Thoracic Oncology and Medicine National Hospital Organization Shikoku Cancer Center  Matsuyama 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