{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T12:41:29Z","timestamp":1778503289675,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"30","license":[{"start":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T00:00:00Z","timestamp":1693612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Malignant pleural mesothelioma (MPM) is associated with previous asbestos exposure, while more clinical insights into this disease have come from other case studies. Maximal cytoreduction is critical in disease control and might help to improve the prognosis. Here, a 41\u2010year\u2010old female presented with a 6\u2010month history of a mass detected in the chest wall following resection of a right pleural mesothelioma 2\u2009years previously. A fluorodeoxyglucose positron emission tomography\/computed tomography scan showed a right chest wall mass with a blurred boundary 8.9\u2009cm\u2009\u00d7\u20093.7\u2009cm in size. The patient had received one\u2009cycle of bevacizumab, carboplatin, and pemetrexed, and two\u2009cycles of nivolumab, ipilimumab, and gemcitabine 5\u2009months before admission. We subsequently resected the tumor, the involved diaphragm, and the fifth and sixth ribs, and titanium mesh and continuous suture were used to close the thoracic cage. The fixed paraffin\u2010embedded tissues showed epithelioid pleural mesothelioma. The patient received nivolumab and ipilimumab postoperatively, and no recurrence was detected 16\u2009months after surgery. En bloc resection with reconstructive surgery effectively removed the locally advanced malignancy and restored the biological function of the thorax with a favorable prognosis. Neoadjuvant immunotherapy might therefore be conducive to radical resection and perioperative immunotherapy might improve the prognosis.<\/jats:p>","DOI":"10.1111\/1759-7714.15095","type":"journal-article","created":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T14:34:50Z","timestamp":1693665290000},"page":"3063-3066","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["En bloc resection of the recurrent pleural mesothelioma and reconstruction of the chest wall after immunotherapy: A case report"],"prefix":"10.1111","volume":"14","author":[{"given":"Changlong","family":"Qin","sequence":"first","affiliation":[{"name":"Lung Cancer Center, West China Hospital Sichuan University  Chengdu People's Republic of China"},{"name":"Lung Cancer Institute, West China Hospital, Sichuan University  Chengdu People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinghong","family":"Xia","sequence":"additional","affiliation":[{"name":"Operating Room of Anesthesia Surgery Center, West China Hospital Sichuan University  Chengdu People's Republic of China"},{"name":"West China School of Nursing Sichuan University  Chengdu People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi\u2010Jia","family":"Chen","sequence":"additional","affiliation":[{"name":"Lung Cancer Center, West China Hospital Sichuan University  Chengdu People's Republic of China"},{"name":"Lung Cancer Institute, West China Hospital, Sichuan University  Chengdu People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinghua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Lung Cancer Center, West China Hospital Sichuan University  Chengdu People's Republic of China"},{"name":"Lung Cancer Institute, West China Hospital, Sichuan University  Chengdu People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9612-4352","authenticated-orcid":false,"given":"Xi","family":"Zheng","sequence":"additional","affiliation":[{"name":"Lung Cancer Center, West China Hospital Sichuan University  Chengdu People's Republic of 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