{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:13:27Z","timestamp":1787789607752,"version":"build-2784847793"},"reference-count":19,"publisher":"Wiley","issue":"34","license":[{"start":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:00:00Z","timestamp":1697760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The localization of lung nodules is challenging during thoracoscopy. In this study, we evaluated the use of three\u2010dimensional (3D) lung reconstruction for use in the operating room to guide the identification of lung nodules during thoracoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center retrospective study. All consecutive patients undergoing thoracoscopic resection of lung nodules were included in the study. Patients were retrospectively divided into two groups based upon whether the thoracoscopic resection was performed with the assistance (3D group) or not (standard group) of 3D lung reconstruction. The operative time (minutes) to detect lung nodules was statistically compared between the two study groups in relation to the characteristics of lung nodules as size, localization, and distance from the visceral pleura.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our study population consisted of 170 patients: 85 in the 3D group and 85 in the standard group. No intergroup difference differences were found regarding the characteristics and histological diagnosis of lesions. The standard group compared to the 3D group was associated with a significantly longer operative time for the detection of lesions &lt;10\u2009mm (13.87\u2009\u00b1\u20092.59 vs. 5.52\u2009\u00b1\u20091.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), lesions between 10 and 20\u2009mm (5.05\u2009\u00b1\u20090.84 vs. 3.89\u2009\u00b1\u20090.92; <jats:italic>p<\/jats:italic>\u2009=\u20090.03), lesions localized in complex segments (7.49\u2009\u00b1\u20094.25 vs. 5.11\u2009\u00b1\u20090.97; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and deep lesions (9.58\u2009\u00b1\u20094.82 vs. 5.4\u2009\u00b1\u20091.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our 3D lung reconstruction model for use in the operating room may be an additional tool for thoracic surgeons to guide the detection of small and deep nodules during thoracoscopy. It is a noninvasive and cost saving procedure and may be widely used.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.15131","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T09:41:10Z","timestamp":1697794870000},"page":"3389-3396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["<scp>Three\u2010dimensional<\/scp> lung reconstructions for the localization of lung nodules to be resected during surgery"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1940-0288","authenticated-orcid":false,"given":"Giovanni","family":"Natale","sequence":"first","affiliation":[{"name":"Thoracic Surgery Unit, Department of Translation Medicine Universit\u00e0 della Campania \u201cLuigiVanvitelli\u201d  Naples 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Filippo","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit, Department of Translation Medicine Universit\u00e0 della Campania \u201cLuigiVanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Chisari","sequence":"additional","affiliation":[{"name":"Genomics and Experimental Oncology Unit, IOM Ricerca  Viagrande Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Raciti","sequence":"additional","affiliation":[{"name":"Genomics and Experimental Oncology Unit, IOM Ricerca  Viagrande Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia Paola","family":"Lombardo","sequence":"additional","affiliation":[{"name":"Genomics and Experimental Oncology Unit, IOM Ricerca  Viagrande Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Mirra","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit, Department of 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