{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:32:06Z","timestamp":1747182726861,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"35","license":[{"start":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:00:00Z","timestamp":1698969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The patient in this report was a 73\u2010year\u2010old male who was diagnosed with small cell lung cancer (T3N0M0 stage IIB) after presenting with a 5.5\u2009cm tumor detected in the right lower lobe of the lung by radiography. After right lower lobectomy and lymphadenectomy, postoperative adjuvant chemotherapy was administered with cisplatin and etoposide. At 27\u2009months after surgery, the patient complained of wheezing. Tracheal metastasis was identified through computed tomography and bronchoscopy. Biopsy confirmed metastasis of small cell lung cancer. Radiotherapy (60\u2009Gy) was administered to the mediastinal lymph nodes, including the supraclavicular region. The patient then underwent four\u2009cycles of carboplatin\u2010etoposide\u2010durvalumab, followed by durvalumab maintenance therapy. At 49\u2009months after surgery, the patient complained of discomfort while speaking, leading to the discovery of a nodule in the subglottic space, which confirmed small cell lung cancer metastasis. Radiotherapy (30\u2009Gy) was administered to the larynx and mediastinum, and the patient continued with durvalumab monotherapy. As of 61\u2009months after surgery, he remains recurrence\u2010free after the second course of radiotherapy. Our favorable outcome could be explained by the synergy between immunotherapy and radiotherapy. Here, we report a rare case of postoperative tracheal metastasis in small cell lung cancer successfully managed with radiotherapy and durvalumab. This shows promise in achieving local disease control and extending survival in postoperative metastatic lesions, highlighting a potential therapeutic approach.<\/jats:p>","DOI":"10.1111\/1759-7714.15143","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T08:23:51Z","timestamp":1698999831000},"page":"3495-3498","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Successful management of postoperative tracheal metastasis in small cell lung cancer with radiotherapy and durvalumab: A case report"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3534-1799","authenticated-orcid":false,"given":"Yasoo","family":"Sugiura","sequence":"first","affiliation":[{"name":"Department of General Thoracic Surgery National Hospital Organization, Kanagawa National Hospital  Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery National Hospital Organization, Kanagawa National Hospital  Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshinori","family":"Hashizume","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery National Hospital Organization, Kanagawa National Hospital  Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2012.792"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.04.1711"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.3.768"},{"issue":"30","key":"e_1_2_7_5_1","article-title":"A rare case of multiple secondary endotracheal metastasis from early stage small cell cancer","volume":"1","author":"Karakattu S","year":"2020","journal-title":"Respir Med Case Rep"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.2715-19"},{"issue":"5","key":"e_1_2_7_7_1","first-page":"422","article-title":"Three cases of postoperative racheal metastasis from lung cancer","volume":"19","author":"Miura T","year":"1997","journal-title":"J Jpn Soc Resp Endosc J"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2482\/haigan.31.275"},{"key":"e_1_2_7_9_1","first-page":"72","article-title":"A Case of Small Cell Carcinoma with Endotracheal Metastasis","volume":"9","author":"Yamamura J","year":"1987","journal-title":"J. Jpn. Soc. Resp. 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