{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:14:52Z","timestamp":1777392892193,"version":"3.51.4"},"reference-count":40,"publisher":"Wiley","issue":"28","license":[{"start":{"date-parts":[[2024,8,18]],"date-time":"2024-08-18T00:00:00Z","timestamp":1723939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072028"],"award-info":[{"award-number":["82072028"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022M711979"],"award-info":[{"award-number":["2022M711979"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate the safety and efficacy of percutaneous biopsy and microwave ablation (B\u2009+\u2009MWA) in patients with pulmonary nodules (PNs) who are receiving antithrombotic therapy by rivaroxaban as bridging therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study comprised 187 patients with PNs who underwent 187 B\u2009+\u2009MWA sessions from January 1, 2020, to December 31, 2021. The enrolled patients were divided into two groups: Group A, who received antithrombotic therapy five days before the procedure and received rivaroxaban as a bridging drug during hospitalization, and group B, who had no antithrombotic treatment. Information about the technical success rate, positive biopsy rate, complete ablative rate, and major complications were collected and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Group A comprised 53 patients and group B comprised 134 patients. The technical success rate was 100% in both groups. The positive biopsy rates were 88.68% and 91.04%, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.6211, X<jats:sup>2<\/jats:sup>\u2009=\u20090.2443). In groups A and B, the complete ablative rates at 6, 12, and 24 months were 100.0% versus 99.25%, 96.23% versus 96.27%, and 88.68% versus 89.55%, respectively. There were no significant differences in bleeding and thrombotic complications between the two groups. No grade 5 complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It is generally considered safe and effective that patients who are on antithrombotic therapy by rivaroxaban as bridging to undergo B\u2009+\u2009MWA for treating PNs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.15425","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T00:05:15Z","timestamp":1724025915000},"page":"1989-1999","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Safety and efficacy of percutaneous biopsy and microwave ablation in patients with pulmonary nodules on antithrombotic therapy: A study with rivaroxaban bridging"],"prefix":"10.1111","volume":"15","author":[{"given":"Nan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Oncology Shandong Provincial Qianfoshan Hospital, Shandong University of Traditional Chinese Medicine  Jinan People's Republic of China"},{"name":"Department of Oncology The First Affiliated Hospital of Shandong First Medical University &amp; Shandong Provincial Qianfoshan Hospital, Shandong Lung Cancer Institute  Jinan People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianyu","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Jining Medical University  Jining People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwen","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Technical Beijing Rheinhealthcare Technology Co., Limited liability company  Beijing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongying","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Hepatology Tai'an Hospital of Traditional Chinese Medicine  Tai'an People's Republic of 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