{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:30:11Z","timestamp":1747182611308,"version":"3.40.5"},"reference-count":11,"publisher":"Wiley","issue":"29","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Lung and bronchus cancer is a leading cause of death in the United States. Compared with the national average, Michigan has an increased mortality rate and low early screening and treatment rates. This study aimed to explore the epidemiological trends and assess overall survival (OS) of patients diagnosed with lung cancer in Michigan from 1996 to 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data was acquired from the Michigan Cancer Surveillance Program (MCSP). Log\u2010rank test was used to test OS among the time periods, univariate and multivariate cox regression models were employed to determine factors that significantly affected OS. We hypothesized that the introduction of more inclusive lung cancer screening guidelines in 2013 would improve OS for patients diagnosed after its implementation and that individual characteristics and tumor characteristics would both affect OS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Notably, 153\u2009742 individuals met inclusion criteria: 54.22% male and 45.78% female. Mean age at diagnosis was 69\u2009years. No significant difference in OS was found among the three time periods (<jats:italic>p<\/jats:italic>\u2009=\u20090.99). Univariate analyses identified four individual characteristics associated with reduced OS: age at diagnosis, male sex, American Indian race, and living in rural or urban area. Reduced OS was associated with primary sites tumors at main bronchus, lung base, or within overlapping lobes, and SEER stage 7.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study highlights several factors that influence OS. Consideration of these factors may be helpful as a community outreach tool to help increase early detection and reduce overall mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.15432","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T06:44:59Z","timestamp":1725518699000},"page":"2110-2115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiological study of overall survivability of individuals diagnosed with lung and bronchus cancer in Michigan between the years 1996 and 2017"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4082-2829","authenticated-orcid":false,"given":"Georgette","family":"Nader","sequence":"first","affiliation":[{"name":"University of Michigan Health Sparrow Hospital\u2010Michigan State University  Lansing Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akhil","family":"Sharma","sequence":"additional","affiliation":[{"name":"University of Michigan Health Sparrow Hospital\u2010Michigan State University  Lansing Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Abdelsamia","sequence":"additional","affiliation":[{"name":"University of Michigan Health Sparrow Hospital\u2010Michigan State University  Lansing Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"University of Michigan Health Sparrow Hospital\u2010Michigan State University  Lansing Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lalitsiri","family":"Atti","sequence":"additional","affiliation":[{"name":"University of Michigan Health Sparrow Hospital\u2010Michigan State University  Lansing Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Laird\u2010Fick","sequence":"additional","affiliation":[{"name":"University of Michigan Health Sparrow Hospital\u2010Michigan State University  Lansing Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"volume-title":"SEER","year":"2024","author":"Common Cancer Sites \u2013 Cancer Stat Facts","key":"e_1_2_10_3_1"},{"volume-title":"State of lung cancer: Michigan State Data","year":"2023","author":"Association, American Lung","key":"e_1_2_10_4_1"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201410-1777CI"},{"key":"e_1_2_10_6_1","unstructured":"Invasive Lung Cancer Incidence by Age at Diagnosis Michigan Residents 1985\u20132020. Invasive Cancer Incidence by Age at Diagnosis. [cited 2024 Mar 17]. Available from:vitalstats.michigan.gov\/osr\/cancer\/candiag.ASP?DxId=IncAgeDiagLung&CoType=0&CoCode=0&AgeID=1"},{"key":"e_1_2_10_7_1","unstructured":"Invasive Lung Cancer Incidence & Mortality Trends Michigan Residents 1985\u20132021. Lung Cancer Incidence and Mortality Trends. [cited 2024 Mar 17]. Available from:vitalstats.michigan.gov\/osr\/cancer\/stateinc.asp?CDxID=IncTrendsLung"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-022-02796-w"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2019-0098"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.12957"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-71996-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgv168"}],"container-title":["Thoracic Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.15432","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T03:09:56Z","timestamp":1728875396000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1759-7714.15432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,4]]},"references-count":11,"journal-issue":{"issue":"29","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/1759-7714.15432"],"URL":"https:\/\/doi.org\/10.1111\/1759-7714.15432","archive":["Portico"],"relation":{},"ISSN":["1759-7706","1759-7714"],"issn-type":[{"type":"print","value":"1759-7706"},{"type":"electronic","value":"1759-7714"}],"subject":[],"published":{"date-parts":[[2024,9,4]]},"assertion":[{"value":"2024-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}