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Three databases were assessed. The primary outcome was overall survival. The secondary outcomes were recurrence\u2010free survival, ipsilateral recurrence, and hospital length of stay (LOS). Hazard ratios (HRs), odds ratios (ORs), and mean difference (MD) with 95% confidence intervals (CIs) were calculated. Reconstruction of time\u2010to\u2010event data and sensitivity analyses were performed for the primary endpoint. After screening, 11 studies were included encompassing 2159 patients undergoing lung metastasectomy (VATS: 827; OT: 1332). Compared to OT, patients who underwent VATS had higher overall survival rates (HR 0.75; 95% CI 0.67\u20130.85; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), no significant difference in recurrence\u2010free survival (HR 1.07; 95% CI 0.88\u20131.29; <jats:italic>p<\/jats:italic>\u2009=\u20090.48), shorter hospital LOS (MD \u22121.99\u2009days; 95% CI \u22122.59 to \u22121.39; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), and no significant difference in ipsilateral recurrence rates (OR 0.86; 95% CI 0.52\u20131.42; <jats:italic>p<\/jats:italic>\u2009=\u20090.56). For patients undergoing pulmonary metastasectomy, VATS strategy is associated with higher survival rates and reduced hospital LOS when compared with OT. Moreover, metastasis recurrence does not seem to be associated with long\u2010term mortality in this population.<\/jats:p>","DOI":"10.1111\/1759-7714.15473","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T04:07:22Z","timestamp":1729224442000},"page":"2401-2407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Video\u2010assisted thoracoscopic surgery versus open thoracotomy for resection of lung metastasis\u2014A meta\u2010analysis of reconstructed time\u2010to\u2010event data"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7381-2806","authenticated-orcid":false,"given":"Felipe S.","family":"Passos","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery MaterDei Hospital  Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro B.","family":"Bregion","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery State University of Campinas  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Fazzini","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences and Public Health University of Cagliari  Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hristo","family":"Kirov","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Jena University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Sandhaus","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Jena University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"von Samson","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Jena University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten","family":"Doenst","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Jena University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tulio","family":"Caldonazo","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Jena University Hospital  Jena Germany"},{"name":"Department of Cardiothoracic Surgery Weil Cornell Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.09.036"},{"issue":"8","key":"e_1_2_11_3_1","first-page":"13571","article-title":"Video\u2010assisted thoracoscopic surgery versus open resection of lung metastases from colorectal cancer","volume":"8","author":"Hou Z","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/1817-1737.114300"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivv309"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1744476"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-021-01460-8"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/ejso.2002.1284"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.03.050"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085329"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-4-13"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.11.031"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1295574"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-013-0284-7"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.07.078"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezx020"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.02.075"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-021-01626-4"},{"key":"e_1_2_11_19_1","unstructured":"WellsG.The Newcastle\u2010Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta\u2010analysis. 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