{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T16:35:00Z","timestamp":1754152500605,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T00:00:00Z","timestamp":1750464000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Currently, no uniform standard exists for the maximum drainage volume permitting chest tube removal following lobectomy in lung cancer patients, and limited research has explored factors influencing postoperative drainage. This study aimed to investigate the relationship between subcutaneous fat area (SFA) and postoperative drainage volume.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective analysis of 509 lung cancer patients who underwent video\u2010assisted thoracoscopic lobectomy. Clinical characteristics, postoperative outcomes (length of stay, hospitalization expenses), blood parameters, chest tube duration, 3\u2010day postoperative drainage volume, and SFA were recorded. Predictive factors for drainage volume were identified using univariate and multivariate logistic regression analyses. SFA was measured at the level of the 12th thoracic vertebra cross\u2010section using preoperative CT imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analysis revealed significant positive correlations between chest tube duration and both length of stay (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and hospitalization expenses (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Chest tube duration (&lt;\u20093 vs. \u2265\u20093\u2009days) was primarily determined by 3\u2010day postoperative drainage volume (574\u2009\u00b1\u2009252 vs. 885\u2009\u00b1\u2009362\u2009mL; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Univariate analysis demonstrated that 3\u2010day postoperative drainage volume correlated with age (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), gender (<jats:italic>p<\/jats:italic>\u2009=\u20090.002), pathological type (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), diabetes (<jats:italic>p<\/jats:italic>\u2009=\u20090.026), hypertension (<jats:italic>p<\/jats:italic>\u2009=\u20090.011), and SFA (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Multivariate logistic regression confirmed that age\u2009\u2265\u200965\u2009years (<jats:italic>p<\/jats:italic>\u2009=\u20090.016), small cell lung cancer (SCLC; <jats:italic>p<\/jats:italic>\u2009=\u20090.022), and SFA\u2009\u2265\u2009100\u2009cm<jats:sup>2<\/jats:sup> (<jats:italic>p<\/jats:italic>\u2009=\u20090.005) were independently associated with postoperative drainage volume\u2009\u2265\u2009650\u2009mL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SFA significantly correlated with 3\u2010day postoperative drainage volume and may serve as a predictor for drainage volume following lobectomy in lung cancer patients. This association highlights its utility in guiding chest tube removal timing and potentially reducing the risk of pleural effusion recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.70114","type":"journal-article","created":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T03:04:04Z","timestamp":1750475044000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Subcutaneous Fat Area Can Be as a Predictors of Drainage Volume After Lobectomy for Lung Cancer"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1863-408X","authenticated-orcid":false,"given":"Jie","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Lung Cancer, Tianjin Medical University Cancer Institute &amp; Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy Tianjin's Clinical Research Center for Cancer  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Lung Cancer, Tianjin Medical University Cancer Institute &amp; Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy Tianjin's Clinical Research Center for Cancer  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaopeng","family":"An","sequence":"additional","affiliation":[{"name":"Tianjin Medical University Cancer Institute &amp; Hospital Tianjin Medical University  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6655-268X","authenticated-orcid":false,"given":"Jie","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Nutrition Therapy, Tianjin Medical University Cancer Institute &amp; Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy Tianjin's Clinical Research Center for Cancer  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.11.036"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2018.12.006"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.09.055"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-023-04920-x"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132008001200004"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00884-1"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.232.55"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(02)01332-7"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezt376"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.06.034"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2015.09.001"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu16172885"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70153-0"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.08.26"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezr126"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2016.08.007"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-017-3975-x"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.01.019"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.06.032"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.12.010"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-021-01479-x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2010.248716"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.10.035"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivu207"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14071430"},{"issue":"7","key":"e_1_2_11_28_1","article-title":"The Effects of Obesity on Lymphatic Pain and Swelling in Breast Cancer Patients","volume":"9","author":"Fu M. 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