{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:47:57Z","timestamp":1758055677890,"version":"3.44.0"},"reference-count":14,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study evaluates the effectiveness and safety of C\u2010arm cone beam CT (CBCT)\u2010guided microcoil localization combined with uniportal video\u2010assisted thoracoscopic surgery (VATS) for the management of small, difficult\u2010to\u2010localize ground\u2010glass opacities (GGOs) and sub\u2010solid nodules in the lungs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed data from 13 patients with single, small, peripheral, non\u2010subpleural GGOs or SSN. All patients underwent successful microcoil localization using CB\u2010CT guidance followed by uniportal VATS resection. A microcoil was positioned partly in the lung parenchyma and partly in the extra\u2010pleural space to assist in intraoperative localization. We evaluated the rate of correct microcoil placement and the technical success of the resection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Microcoil placement was successfully performed in all patients, with an average procedure time of 28.8\u2009\u00b1\u200910.8\u2009min. The mean nodule size was 9.9\u2009\u00b1\u20095.4\u2009mm, and 76.9% of the nodules were classified as ground\u2010glass opacities. No intraparenchymal bleeding was observed, and four patients (30.8%) experienced pneumothorax, all of which were self\u2010limited and required no intervention or coil repositioning. The uniVATS resection success rate was 100%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CBCT\u2010guided microcoil localization, with partial placement of the coil in the extra\u2010pleural space, proved to be a highly effective technique for the localization and resection of small pulmonary nodules. The procedure demonstrated high accuracy, minimal complications, reduction of procedural time, and short hospital stays. Intraoperative fluoroscopy was never necessary, with a high reduction in radiation exposure for the patient and the operator. Further studies with larger populations and longer follow\u2010ups are needed to validate these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.70152","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T02:46:36Z","timestamp":1756953996000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["C\u2010Arm Cone Beam <scp>CT<\/scp>\u2010Guided Preoperative Microcoil Pulmonary Ground Glass Nodule Localization: Diagnostic and Surgical Advantage"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0919-1504","authenticated-orcid":false,"given":"Carlo","family":"Altomare","sequence":"first","affiliation":[{"name":"Unit of Diagnostic Imaging and Interventional Radiology Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Casati","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Imaging and Interventional Radiology, Department of Medicine and Surgery Universit\u00e0 Campus Bio\u2010Medico di Roma  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppina","family":"Pacella","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Imaging and Interventional Radiology Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Olivieri","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Imaging and Interventional Radiology, Department of Medicine and Surgery Universit\u00e0 Campus Bio\u2010Medico di Roma  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Tirabasso","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Epidemiology and Hygiene National Institute for Insurance Against Accidents at Work  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annamaria","family":"Altomare","sequence":"additional","affiliation":[{"name":"Unit of Gastroenterology Universit\u00e0 Campus Bio\u2010Medico di Roma  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Frasca","sequence":"additional","affiliation":[{"name":"Unit of Thoracic Surgery Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Longo","sequence":"additional","affiliation":[{"name":"Unit of Thoracic Surgery Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierfilippo","family":"Crucitti","sequence":"additional","affiliation":[{"name":"Unit of Thoracic Surgery Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"},{"name":"Unit of Thoracic Surgery, Department of Medicine and Surgery Universit\u00e0 Campus Bio\u2010Medico di Roma  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliodoro","family":"Faiella","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Imaging and Interventional Radiology Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Beomonte Zobel","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Imaging and Interventional Radiology Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"},{"name":"Unit of Diagnostic Imaging and Interventional Radiology, Department of Medicine and Surgery Universit\u00e0 Campus Bio\u2010Medico di Roma  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario Francesco","family":"Grasso","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Imaging and Interventional Radiology Fondazione Policlinico Universitario Campus Bio\u2010Medico  Rome Italy"},{"name":"Unit of Diagnostic Imaging and Interventional Radiology, Department of Medicine and Surgery Universit\u00e0 Campus Bio\u2010Medico di Roma  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,3]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"U.S. National Library of Medicine \u201cMedlinePlus. 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