{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T09:58:59Z","timestamp":1766483939461,"version":"3.48.0"},"reference-count":32,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Intentional pulmonary segmentectomy via minimally invasive surgery is now commonly used to treat early stage non\u2010small cell lung cancers smaller than 2\u2009cm. The main challenge of this procedure lies in identifying the intersegmental plane (ISP). Two primary methods are used: the method of inflation\u2013deflation (MID) and indocyanine green (ICG) fluorescence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective, single\u2010center study included 196 patients who underwent minimally invasive segmentectomy between January 2022 and December 2024. The ISP was identified using both MID and ICG injection. Patients were divided into two groups based on whether the discrepancy between the two methods was \u2264\u200910\u2009mm or &gt;\u200910\u2009mm, in order to identify factors associated with discordance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A discrepancy &gt;\u200910\u2009mm was observed in 41.3% of cases (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200981). Factors significantly associated with this discordance included pleuropulmonary adhesions (OR\u2009=\u20094.61;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.032), complex segmentectomies (OR\u2009=\u20092.36;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027), and bronchial variations (OR\u2009=\u20093.72;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011). ICG visualization of the ISP was rated satisfactory or very satisfactory (score \u2265\u20092) in 88.8% of cases. No significant differences were observed in postoperative outcomes, complications, or resection margin quality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ICG proves to be a reliable and reproducible method for ISP visualization, though it has limitations in certain clinical situations. It remains a valuable tool, especially during the learning phase or in cases of anatomical uncertainty, and should be adapted to each patient's anatomy, the type of segmentectomy, and the surgeon's experience.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.70211","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T14:12:56Z","timestamp":1766153576000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors Influencing the Effectiveness of Fluorescence in Determining the Intersegmental Plane During Intentional Pulmonary Segmentectomy: Results of a Prospective Study on 196 Patients"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0206-3328","authenticated-orcid":false,"given":"Quentin","family":"Rudondy","sequence":"first","affiliation":[{"name":"University of Cote d'Azur  Nice France"},{"name":"Department of Thoracic Surgery Pasteur 1 Hospital, University Hospital of Nice  Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Martinet\u2010Kosinski","sequence":"additional","affiliation":[{"name":"Department of Digestive and Hepato\u2010Biliary Surgery University Hospital of Clermont\u2010Ferrand  Clermont\u2010Ferrand France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayeb","family":"Benkiran","sequence":"additional","affiliation":[{"name":"University of Cote d'Azur  Nice France"},{"name":"Department of Thoracic Surgery Pasteur 1 Hospital, University Hospital of Nice  Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Pasteur 1 Hospital, University Hospital of Nice  Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abel","family":"Gomez\u2010Caro","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Pasteur 1 Hospital, University Hospital of Nice  Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5585-7245","authenticated-orcid":false,"given":"Sebastien","family":"Frey","sequence":"additional","affiliation":[{"name":"University of Cote d'Azur  Nice France"},{"name":"Department of General Surgery Pasteur 2 Hospital, University Hospital of Nice  Nice France"},{"name":"University of Cote d'Azur, Inria, Epione Team  Sophia\u2010Antipolis France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Phillippe","family":"Berthet","sequence":"additional","affiliation":[{"name":"University of Cote d'Azur  Nice France"},{"name":"Department of Thoracic Surgery Pasteur 1 Hospital, University Hospital of Nice  Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000673"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00537-U"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/jovs.2017.05.10"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/EVIDoa2100016"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X241249182"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02333-3"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2212083"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00184308"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.05.052"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13192"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.15274"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.09.020"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-017-0878-6"},{"issue":"24","key":"e_1_2_11_16_1","article-title":"Real\u2010Time Image\u2010Guided Indocyanine Green Fluorescence Dual\u2010Visualization Technique to Measure the Intraoperative Resection Margin During Thoracoscopic Segmentectomy","author":"Sun Y.","year":"2022","journal-title":"Asia\u2010Pacific Journal of Clinical Oncology"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xjtc.2020.12.005"},{"issue":"7","key":"e_1_2_11_18_1","first-page":"501","article-title":"Thoracoscopic Segmentectomy Using Three\u2010Dimensional Computed Tomography and Indocyanine\u2010Green Fluorescence Navigation","volume":"72","author":"Ichinose J.","year":"2019","journal-title":"Kyobu Geka"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.04.84"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.07.020"},{"volume-title":"Indocyanine Green (ICG) Angiography","year":"2025","author":"Muraleedharan 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