{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T05:05:26Z","timestamp":1770959126120,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anatomical sublobar resection (ASR) is non\u2010inferior to lobectomy for peripheral small\u2010sized lung cancer. However, for nodules located in complex locations, ASR is usually challenging. This study aimed to compare the outcomes of ASR and lobectomy for multi\u2010intersegmental pulmonary nodules.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with pulmonary nodules (\u2264\u20092\u2009cm) who underwent ASR or lobectomy between 2012 and 2023 were retrospectively screened. The 3D multiplanar reconstruction software was used to determine the precise tumor localization. Demographic, radiomic, histopathologic, and perioperative characteristics between ASR and lobectomy were compared. The log rank test was adopted for prognostic evaluation. Propensity score\u2010matching (PSM) analysis was conducted to yield matched patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 93 patients undergoing ASR and 118 subjects undergoing lobectomy were included. Patients with ASR were younger and had a smaller tumor size, fewer solid nodules, and more central nodules than those with lobectomy. ASR achieved a median surgical margin of 2.0\u2009cm, removed fewer lymph nodes, and preserved seven more subsegments than lobectomy (5 vs. 12,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), without increasing air leak or postoperative hospital stay. During a median follow\u2010up of 32 months, four patients in the lobectomy group encountered tumor recurrence, whereas no recurrence occurred in the ASR group. The 5\u2010year recurrence\u2010free survival (RFS) after lobectomy and ASR was 95.4% and 100%, respectively. After PSM, 34 matched patients remained in each group, and the RFS was 100% in both groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ASR is feasible for multi\u2010intersegmental nodules and can preserve more pulmonary parenchyma with no compromise in perioperative and oncological outcomes compared to lobectomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.70216","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T07:14:48Z","timestamp":1769670888000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anatomical Sublobar Resection for Multi\u2010Intersegmental Pulmonary Nodules"],"prefix":"10.1111","volume":"17","author":[{"given":"Xianglong","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengzhe","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University  Nanjing China"},{"name":"Department of Thoracic Surgery The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University  Xuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4820-4603","authenticated-orcid":false,"given":"Zhihua","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenzheng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weibing","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00537-U"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.06.010"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.8762"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02333-3"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2212083"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2021.08.035"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivac218"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1722172"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2023.05.021"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.12897"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2020.10.083"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr-22-391"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2016.09.43"},{"issue":"3","key":"e_1_2_12_15_1","first-page":"518","article-title":"Locoregional Recurrence After Segmentectomy for Clinical\u2010T1aN0M0 Radiologically Solid Non\u2010Small\u2010Cell Lung Carcinoma","volume":"51","author":"Hattori A.","year":"2017","journal-title":"European Association for Cardio\u2010Thoracic Surgery"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2024.10.002"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-019-0831-0"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.233244"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2024.108541"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.05.052"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-6-17"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2020.09.036"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr-21-661"}],"container-title":["Thoracic Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.70216","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1759-7714.70216","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.70216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T04:18:01Z","timestamp":1770956281000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1759-7714.70216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,28]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/1759-7714.70216"],"URL":"https:\/\/doi.org\/10.1111\/1759-7714.70216","archive":["Portico"],"relation":{},"ISSN":["1759-7706","1759-7714"],"issn-type":[{"value":"1759-7706","type":"print"},{"value":"1759-7714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,28]]},"assertion":[{"value":"2025-09-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70216"}}