{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:39:47Z","timestamp":1772987987149,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2508605"],"award-info":[{"award-number":["2023YFC2508605"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Cryoablation has proved to be an effective method to cure lung cancer based upon existing research, thus has been widely used in clinical practice. This pilot study aimed to evaluate the efficacy and safety of CT\u2010guided cryoablation for the treatment of different lung tumors, including solid and sub\u2010solid lung tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study enrolled a total of 77 patients with lung tumors, comprising 46 solid tumors and 31 sub\u2010solid tumors. All patients underwent CT\u2010guided cryoablation. The various aspects of the treatment, including procedural details, technical success rate, complications, and local tumor control were systematically evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The technical success rate of CT\u2010guided cryoablation was 100%. The procedure was well\u2010tolerated, with a low rate of major complications (4%). The most common complication is pneumothorax, which presents in 34.8% of patients with solid tumors as well as 51.6% of patients with sub\u2010solid tumors. The incidence rates of all the complications were not statistically different. The median follow\u2010up period was 24\u2009months, during which local tumor control rates were 74% for solid lung tumors and 100% for sub\u2010solid tumors. The overall survival rates at 24\u2009months were 100%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CT\u2010guided cryoablation appears to be an effective and safe treatment modality for different lung tumors, including solid and sub\u2010solid tumors. The high technical success rate, low rate of major complications, and favorable local tumor control suggest that cryoablation could serve as a valuable alternative treatment especially for the tumors manifesting as sub\u2010solid tumors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.70253","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T11:42:33Z","timestamp":1771587753000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>CT<\/scp>\n                    \u2010Guided Cryoablation Achieves Significantly Higher Local Tumor Control in Sub\u2010Solid Lung Tumors Compared With Solid Tumors: A Retrospective Cohort Study"],"prefix":"10.1111","volume":"17","author":[{"given":"Tongyin","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Radiology China\u2010Japan Friendship Hospital  Beijing 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National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine China\u2010Japan Friendship Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongliang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Radiology China\u2010Japan Friendship Hospital  Beijing 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