{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T03:52:29Z","timestamp":1781581949098,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L252215"],"award-info":[{"award-number":["L252215"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To characterize perioperative outcomes and quantify the relative contribution of patient\u2010related versus procedure\u2010related factors to short\u2010term recovery (LOS and CTD) in octogenarians undergoing minimally invasive lung resection within an ERAS pathway.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We reviewed 106 consecutive patients aged 80\u2009years or older with suspected primary NSCLC who underwent video\u2010assisted or robotic\u2010assisted resection (2020\u20132025) under standardized ERAS care. Primary outcomes were LOS and CTD. Determinants were assessed with multivariable linear models of log(LOS\u2009+\u20091) and log(CTD\u2009+\u20091) among malignant survivors (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200999).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Median age was 81\u2009years (IQR 80\u201383); 57.5% were men. Procedures included wedge resection (52.8%), segmentectomy (9.4%), and lobectomy (37.7%); 96.2% were VATS and 3.8% RATS. Median LOS was 4.0\u2009days (IQR 3.0\u20135.8) and CTD 3.0\u2009days (IQR 1.0\u20134.0). Complications occurred in 13.2%, and perioperative mortality was 0.9%. Sublobar resection (vs. lobectomy) was independently associated with shorter LOS (standardized beta \u22120.262,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011) and CTD (standardized beta \u22120.326,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Age was not associated with LOS, but showed a small inverse association with CTD (standardized beta \u22120.219,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018). No patient was readmitted within 30\u2009days, chest tube reinsertion occurred in 1 patient (0.9%), and 10 patients (9.4%) were transferred to lower\u2010level hospitals after discharge.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In carefully selected octogenarians managed with minimally invasive surgery and ERAS, surgical invasiveness (extent of resection) was the dominant modifiable driver of recovery, whereas chronological age alone provided limited incremental discrimination of recovery speed. Favorable in\u2010hospital recovery was not associated with increased short\u2010term adverse events after discharge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.70287","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T11:05:46Z","timestamp":1779966346000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Surgical Invasiveness Trumps Chronological Age: Determinants of Short\u2010Term Recovery in Octogenarian Lung Cancer Patients"],"prefix":"10.1111","volume":"17","author":[{"given":"Qixuan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery Peking Union Medical College Hospital, Chinese Academy of Medical Science  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Peking Union Medical College Hospital, Chinese Academy of Medical Science  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4188-9638","authenticated-orcid":false,"given":"Hongsheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Peking Union Medical College Hospital, Chinese Academy of Medical Science  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingzhi","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Peking Union Medical College Hospital, Chinese Academy of Medical Science  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhewei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Peking Union Medical College Hospital, Chinese Academy of Medical Science  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongjie","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Peking Union Medical College Hospital, Chinese Academy of Medical Science  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/ccts\u201022\u201012"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2359"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivt034"},{"issue":"2","key":"e_1_2_13_6_1","first-page":"204","article-title":"Surgery for Lung Tumors in the Elderly: A Retrospective Observational Study","volume":"9","author":"Stamenovic D.","year":"2018","journal-title":"Journal of Geriatric 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