{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T08:47:41Z","timestamp":1792054061926,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>For the repair of chest wall defects, three\u2010dimensional\u2010printed PEEK implants show great potential due to their excellent anatomical matching and mechanical properties. However, Quality\u2010Of\u2010Life assessments after using these implants in chest wall reconstruction remain underexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study included 20 patients who underwent chest wall defect reconstruction with 3D\u2010printed PEEK implants at our center between April 2017 and June 2024 and were followed up long\u2010term. Clinical data collected at various time points included safety indicators (long\u2010term adverse reactions, blood routine, hepatic and renal function), respiratory function assessments (pulmonary function tests, arterial blood gas analysis), Quality\u2010Of\u2010Life indicators (SF\u201036 health survey).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Through a median follow\u2010up of 35.3\u2009months, we found that personalized PEEK thoracic rib implants achieved precise anatomical reconstruction and effective respiratory dynamics maintenance. Complete recovery of preoperative hematological parameters (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05) and liver\/kidney function confirmed their biochemical safety. \u2265\u20091\u2009year after surgery, the restrictive ventilation function of the patients was still lower than that before the operation, and the CO\n                      <jats:sub>2<\/jats:sub>\n                      excretion increased (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), but the alveolar ventilation function wasn't impaired. Oxygenation was normal (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). The patient's physical health scores (SF\u201036 PCS) remained unchanged from preoperative levels (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05), while psychosocial functioning (SF\u201036 MCS) showed significant improvement (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>3D\u2010printed PEEK implants used in chest wall reconstruction exhibited favorable safety and were associated with improved long\u2010term Quality Of Life. These findings support that PEEK reconstruction may contribute to a combined benefit of disease control, functional preservation, and psychological recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.70323","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T01:41:52Z","timestamp":1781746912000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Long\u2010Term Quality of Life Study for Patients Received Chest Wall Reconstruction by Using\n                    <scp>3D<\/scp>\n                    \u2010Printed\n                    <scp>PEEK<\/scp>\n                    Implants"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6326-1123","authenticated-orcid":false,"given":"Ge","family":"Li","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery Tangdu Hospital, The Fourth Military Medical University  Xi'an China"},{"name":"Department I of Thoracic Oncology Peking University Cancer Hospital &amp; Institute  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tangdu Hospital, The Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tangdu Hospital, The Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangfan","family":"Huo","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tangdu Hospital, The Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghai","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tangdu Hospital, The Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanquan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tangdu Hospital, The Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minglei","family":"Zhuo","sequence":"additional","affiliation":[{"name":"Department I of Thoracic Oncology Peking University Cancer Hospital &amp; Institute  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tangdu Hospital, The Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.11.012"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1726-4901(09)70276-X"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2015.00247"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-020-1064-y"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2015.07.013"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-023-14765-w"},{"issue":"7","key":"e_1_2_11_8_1","first-page":"438","article-title":"Advances in Surgical Treatment of Chest Wall Tumors","volume":"40","author":"Jiang H.","year":"2024","journal-title":"Chinese Journal of Thoracic and Cardiovascular Surgery"},{"key":"e_1_2_11_9_1","first-page":"325","article-title":"2022 Chinese Expert Consensus on Perioperative and Comprehensive Management of Mediastinal and Chest Wall Tumors","volume":"30","author":"Chinese Medical Doctor Association Thoracic Surgeon Branch","year":"2023","journal-title":"Chinese Journal of Clinical Thoracic and Cardiovascular Surgery"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr-21-935"},{"issue":"1","key":"e_1_2_11_11_1","first-page":"1","article-title":"Chinese Expert Consensus on Chest Wall Tumor Resection and Reconstruction Surgery (2018 Edition)","volume":"26","author":"Chinese Expert Consensus Group on Chest Wall Tumors","year":"2019","journal-title":"Chinese Journal of Clinical Thoracic and Cardiovascular Surgery"},{"issue":"3","key":"e_1_2_11_12_1","first-page":"151","article-title":"Fabrication, Microstructure and Properties of Advanced Ceramic\u2010Reinforced Composites for Dental Implants: A Review","volume":"4","author":"Thanigachalam M.","year":"2023","journal-title":"Biomaterials Translational"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1TB01349A"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.18063\/ijb.v8i4.615"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.02.064"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.108757"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.09.044"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13560"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.24823"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2020.09.175"},{"key":"e_1_2_11_21_1","doi-asserted-by":"crossref","unstructured":"\u201cPatient\u2010Reported Outcome Measures for Emotional Functioning in Cancer Patients: Content Comparison of the EORTC CAT Core FACT\u2010G HADS SF\u201036 PRO\u2010CTCAE and PROMIS Instruments\u2010Rothmund\u20102023\u2010Psycho\u2010Oncology\u2010Wiley Online Library \u201dhttps:\/\/doi.org\/10.1002\/pon.6109.","DOI":"10.1002\/pon.6109"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1993.11.3.570"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-020-02421-9"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073191111411667"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju244"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2004.12.008"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6890.1437"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.307.6896.126-b"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.6109"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-024-02659-0"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2021.07.103"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2019.05.040"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezad348"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0019-y"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-23-621"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.07.001"},{"key":"e_1_2_11_37_1","unstructured":"\u201cNational Children's Tumor Surveillance Annual Report. 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