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Thirteen months after surgery, she developed coughing, wheezing, and shortness of breath. Chest CT revealed stenosis in the right main and middle bronchi with a soft\u2010tissue density lesion. No suspicious metastatic lesions were observed around the airways, and the analysis of bronchoscopic biopsy specimens confirmed a rare endobronchial metastasis of osteosarcoma. Despite bronchoscopic intervention, the patient eventually died due to late detection and rapid tumor progression. 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