{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T07:05:45Z","timestamp":1789455945880,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Herein, we reported the use of Intraoperative\u2010Contrast Enhanced Ultrasonography (Io\u2010CEUS) during Robotic Assisted Thoracic Surgery (RATS) for identification of malignant lung nodule that was missed during previous operation. Pre\u2010operative CT scan with 3D reconstruction defined the prompt position of the target lesion within S8 segment of right lower lobe and the anatomic landmarks as the distance from interlobar fissure and diaphragm. The lesion was then successfully detected by Io\u2010CEUS. The different arterial enhancement observed during wash\u2010in (hyperenhancement) and wash\u2010out (hypo\u2010enhancement) phases helped to differentiate the nodule from lung parenchyma. The lesion was resected by mechanical stapler and frozen section analysis diagnosed metastasis from colon carcinoma. Post\u2010operative course was unremarkable; patient was discharged on post\u2010operative day 3.<\/jats:p>","DOI":"10.1111\/1759-7714.70377","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:42:48Z","timestamp":1787748168000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative Contrast\u2010Enhanced Ultrasonography (Io\u2010\n                    <scp>CEUS<\/scp>\n                    ) to Detect Missed Lung Nodules During Robot\u2010Assisted Thoracoscopic Surgery"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0628-613X","authenticated-orcid":false,"given":"Alfonso","family":"Fiorelli","sequence":"first","affiliation":[{"name":"Thoracic Surgery Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3499-196X","authenticated-orcid":false,"given":"Antonio","family":"Marella","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3676-0664","authenticated-orcid":false,"given":"Marco","family":"Aiello","sequence":"additional","affiliation":[{"name":"IRCCS Synlab SDN  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6232-7645","authenticated-orcid":false,"given":"Valentina","family":"Brancato","sequence":"additional","affiliation":[{"name":"IRCCS Synlab SDN  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9734-7702","authenticated-orcid":false,"given":"Marco","family":"Salvatore","sequence":"additional","affiliation":[{"name":"IRCCS Synlab SDN  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Comunale","sequence":"additional","affiliation":[{"name":"Oncology Unit Salerno Hospital  Salerno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Ferrigno","sequence":"additional","affiliation":[{"name":"ASL SA  Salerno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5129-7201","authenticated-orcid":false,"given":"Gaetana","family":"Messina","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2023.04.006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.15131"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.03.157"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1708836"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.08.065"},{"key":"e_1_2_10_7_1","unstructured":"https:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf22\/K223830.pdf."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.11152\/mu-1053"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xjtc.2025.01.028"},{"key":"e_1_2_10_10_1","article-title":"The Role of Contrast\u2010Enhanced Ultrasound in Selection Indication and Improveing Diagnosis for Transthoracic Biopsy in Peripheral Pulmonary and Mediastinal Lesions","volume":"2015","author":"Wang S.","year":"2015","journal-title":"BioMed Research International"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.230171"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1556\/imas.5.2013.1.6"}],"container-title":["Thoracic Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.70377","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1759-7714.70377","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.70377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:11:54Z","timestamp":1789452714000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1759-7714.70377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":11,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/1759-7714.70377"],"URL":"https:\/\/doi.org\/10.1111\/1759-7714.70377","archive":["Portico"],"relation":{},"ISSN":["1759-7706","1759-7714"],"issn-type":[{"value":"1759-7706","type":"print"},{"value":"1759-7714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,26]]},"assertion":[{"value":"2026-04-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70377"}}