{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:50:25Z","timestamp":1792144225730,"version":"4.4.0"},"reference-count":29,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Precise localization is critical for sublobar resection of small pulmonary nodules. We evaluated the safety, technical efficiency, and clinical outcomes of preoperative percutaneous dye\u2010localization using a cone\u2010beam computed tomography (CBCT)\u2010enabled flat\u2010panel detector interventional fluoroscopy system in a hybrid operating room (HOR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed 74 consecutive patients (137 lesions) who underwent image\u2010guided localization followed by video\u2010assisted thoracoscopic surgery (VATS) sublobar resection (wedge resection or segmentectomy) between 2022 and 2023 at Chia\u2010Yi Christian Hospital. Procedural workflow, localization success, surgical margins, and perioperative outcomes were systematically analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Technical localization success was achieved in 100% of lesions (mean nodule diameter: 8.59\u2009\u00b1\u20094.85\u2009mm). The procedure required a mean of 1.31\u2009\u00b1\u20090.67 puncture attempts per lesion at a mean depth of 5.22\u2009\u00b1\u20091.86\u2009cm. Procedure\u2010related pneumothorax occurred in 29.7% (22\/74) of patients, with 14.9% (11\/74) requiring pigtail catheter drainage; pneumothorax occurrence was significantly associated with multiple puncture attempts (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and lower\u2010lobe lesions (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Lower\u2010lobe location was significantly associated with requiring more puncture attempts (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.028). For malignant lesions, the mean pathological resection margin was 17.16\u2009\u00b1\u20098.73\u2009mm, with 92.31% achieving a margin\u2010to\u2010tumor ratio (MTR)\u2009\u2265\u20091. The mean postoperative hospital stay was 3.04\u2009\u00b1\u20091.16\u2009days.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Single\u2010stage image\u2010guided dye\u2010localization and VATS sublobar lung resection in an HOR using a biplane CBCT\u2010enabled platform is safe, feasible, and effective. This streamlined workflow ensures high technical success and adequate surgical margins with manageable complications. Further studies are warranted to evaluate long\u2010term oncological outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.70401","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:39:35Z","timestamp":1792143575000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nodule Dye\u2010Localization Using Interventional Fluoroscopy for Image\u2010Guided Sublobar Lung Resection"],"prefix":"10.1111","volume":"17","author":[{"given":"Yueh\u2010Lin","family":"Wu","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, Department of Surgery Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kam\u2010Hong","family":"Kam","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Department of Surgery Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi Taiwan"},{"name":"Department of Biomedical Sciences National Chung Cheng University  Chia\u2010Yi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi\u2010Yen","family":"Liang","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Internal Medicine Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Ting","family":"Lai","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Internal Medicine Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tien\u2010Hsin","family":"Jeng","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Internal Medicine Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang\u2010Ching","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Internal Medicine Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u2010Fen","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Department of Surgery Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9406-2880","authenticated-orcid":false,"given":"Yung\u2010Cheng","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Surgery Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi 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