{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T08:27:17Z","timestamp":1793262437266,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T00:00:00Z","timestamp":1703894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["F32AI149950"],"award-info":[{"award-number":["F32AI149950"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["K01AI175527"],"award-info":[{"award-number":["K01AI175527"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI146849"],"award-info":[{"award-number":["R01AI146849"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["besjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Methods Ecol Evol"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:list>\n                      <jats:list-item>\n                        <jats:p>Measuring vector\u2013human contact in a natural setting can inform precise targeting of interventions to interrupt transmission of vector\u2010borne diseases. One approach is to directly match human DNA in vector bloodmeals to the individuals who were bitten using genotype panels of discriminative short tandem repeats (STRs). Existing methods for matching STR profiles in bloodmeals to the people bitten preclude the ability to match most incomplete profiles and multisource bloodmeals to bitten individuals.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>We developed bistro, an R package that implements three pre\u2010existing STR matching methods as well as the package's namesake, bistro, a new algorithm described here. bistro employs forensic analysis methods to calculate likelihood ratios and match human STR profiles in bloodmeals to people using a dynamic threshold. We evaluated the algorithm's accuracy and compared it to existing matching approaches using a publicly available panel of 188 single\u2010source and 100 multisource samples containing DNA from 50 known human sources. Then, we applied it to match 777 newly field\u2010collected mosquito bloodmeals to a database of 645 people.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>The R package implements four STR matching algorithms in user\u2010friendly functions with clear documentation. bistro correctly matched 99% (187\/188) of profiles in single\u2010source samples, and 62% (224\/359) of profiles from multisource samples, resulting in a sensitivity of 0.75 (vs. &lt;0.51 for other algorithms). The specificity of bistro was 0.9998 (vs. 1 for other algorithms). Furthermore, bistro identified 79% (720\/906) of all possible matches for field\u2010derived mosquitoes, yielding 1.4\u00d7 more matches than existing algorithms.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>bistro identifies more correct bloodmeal\u2013human matches than existing approaches, enabling more accurate and robust analyses of vector\u2013human contact in natural settings. The bistro R package and corresponding documentation allow for straightforward uptake of this algorithm by others.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1111\/2041-210x.14277","type":"journal-article","created":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T05:09:05Z","timestamp":1703912945000},"page":"308-316","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["bistro: An R package for vector bloodmeal identification by short tandem repeat overlap"],"prefix":"10.1111","volume":"15","author":[{"given":"Zena","family":"Lapp","sequence":"first","affiliation":[{"name":"Duke Global Health Institute, Duke University  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Abel","sequence":"additional","affiliation":[{"name":"Academic Model Providing Access to Healthcare (AMPATH)  Eldoret Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Mangeni","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Medical Statistics, School of Public Health Moi University  Eldoret Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew A.","family":"Obala","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences Moi University  Eldoret Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy P.","family":"O'Meara","sequence":"additional","affiliation":[{"name":"Duke Global Health Institute, Duke University  Durham North Carolina USA"},{"name":"Division of Infectious Diseases, School of Medicine Duke University  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve M.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Duke Global Health Institute, Duke University  Durham North Carolina USA"},{"name":"Division of Infectious Diseases, School of Medicine Duke University  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5742-8847","authenticated-orcid":false,"given":"Christine F.","family":"Markwalter","sequence":"additional","affiliation":[{"name":"Duke Global Health Institute, Duke University  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,30]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Ahlmann\u2010Eltze C.(2020).ggupset: Combination matrix axis for \u2018ggplot2\u2019 to create \u2018UpSet\u2019 plots(0.3.0) [computer software].https:\/\/cran.rstudio.com\/web\/packages\/ggupset\/index.html"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsigen.2017.10.006"},{"key":"e_1_2_11_4_1","unstructured":"Bengtsson H.(2022).R.utils: Various programming utilities(2.12.2) [computer software].https:\/\/cran.r\u2010project.org\/web\/packages\/R.utils\/index.html"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsigen.2016.07.016"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsigss.2017.09.160"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsigen.2019.03.024"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010017\u201001270\u20104"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsigen.2012.12.004"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004706"},{"key":"e_1_2_11_11_1","unstructured":"Kassambara A.(2018).ggpubr: \u2018ggplot2\u2019 based publication ready plots(0.2) [computer software].https:\/\/CRAN.R\u2010project.org\/package=ggpubr"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.21\u20100210"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts480"},{"key":"e_1_2_11_14_1","unstructured":"Lapp Z. &Markwalter C. F.(2023).duke\u2010malaria\u2010collaboratory\/bistro: v0.2.0.Zenodo https:\/\/doi.org\/10.5281\/zenodo.8329908"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0000807"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010023\u201004541\u20102"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1520\/JFS15018J"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1603\/0022\u20102585\u201041.4.803"},{"key":"e_1_2_11_19_1","unstructured":"NCBI NLM NIH & US DHHS. (2021).Osiris (open source independent review and interpretation system)(2.15.1) [computer software].https:\/\/www.ncbi.nlm.nih.gov\/osiris\/"},{"key":"e_1_2_11_20_1","unstructured":"Oyvind Bleka. (2023).euroformix: A quantitative model for interpreting DNA mixtures[computer software].http:\/\/www.euroformix.com\/"},{"key":"e_1_2_11_21_1","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2021"},{"key":"e_1_2_11_22_1","unstructured":"RStudio. (2023).RStudio: Integrated Development Environment for R.https:\/\/www.rstudio.com\/"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20103156.2004.01250.x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsigen.2017.08.011"},{"key":"e_1_2_11_25_1","unstructured":"Tierney L.(2023).codetools: Code analysis tools for R(0.2\u201019) [computer software].https:\/\/cran.r\u2010project.org\/web\/packages\/codetools\/index.html"},{"key":"e_1_2_11_26_1","unstructured":"WHO. (2020).Vector\u2010borne diseases.https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/vector\u2010borne\u2010diseases"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.01686"}],"container-title":["Methods in Ecology and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/besjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/2041-210X.14277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T01:28:29Z","timestamp":1707269309000},"score":1,"resource":{"primary":{"URL":"https:\/\/besjournals.onlinelibrary.wiley.com\/doi\/10.1111\/2041-210X.14277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,30]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1111\/2041-210X.14277"],"URL":"https:\/\/doi.org\/10.1111\/2041-210x.14277","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/2041-210X.14277\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/2041-210X.14277\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/2041-210X.14277\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/2041-210X.14277\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/2041-210X.14277\/v2\/decision1","asserted-by":"object"}],"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.09.14.23295566","asserted-by":"object"}]},"ISSN":["2041-210X","2041-210X"],"issn-type":[{"value":"2041-210X","type":"print"},{"value":"2041-210X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,30]]},"assertion":[{"value":"2023-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}