{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:29:53Z","timestamp":1767652193925},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T00:00:00Z","timestamp":1161907200000},"content-version":"vor","delay-in-days":5382,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Microbiology"],"published-print":{"date-parts":[[1992,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Chitin, the \u03b21,4\u2010linked polymer of <jats:italic>N<\/jats:italic>\u2010acetylglucosamine, is a fibrous polysaccharide that in many yeasts helps to maintain the structure of the mother\u2010bud junction and in filamentous fungi is often the major supporting component of the cell wall. We have previously described a <jats:italic>Candida albicans<\/jats:italic> chitin synthase, CHS1. The DNA and derived protein sequences of a second gene, CHS2, are presented and compared with previously published gene sequences. Northern blot analysis shows that strikingly different levels of synthase 1 and 2 expression occur during yeast and hyphal phases of <jats:italic>Candida<\/jats:italic> growth.<\/jats:p>","DOI":"10.1111\/j.1365-2958.1992.tb01494.x","type":"journal-article","created":{"date-parts":[[2006,10,28]],"date-time":"2006-10-28T00:24:03Z","timestamp":1161995043000},"page":"497-502","source":"Crossref","is-referenced-by-count":79,"title":["Expression of chitin synthase genes during yeast and hyphal growth phases of <i>Candida albicans<\/i>"],"prefix":"10.1111","volume":"6","author":[{"given":"J. L.","family":"Chen\u2010Wu","sequence":"first","affiliation":[]},{"given":"J.","family":"Zwicker","sequence":"additional","affiliation":[]},{"given":"A. R.","family":"Bowen","sequence":"additional","affiliation":[]},{"given":"P. W.","family":"Robbins","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,10,27]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.112.541.test"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1990.tb00587.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.2.519"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.19.7424"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.108.5.1665"},{"key":"e_1_2_1_7_1","first-page":"635","article-title":"Cell wall of pathogenic yeasts and implications for antimycotic therapy","volume":"12","author":"Cassone A.","year":"1986","journal-title":"Drugs Exptl Clin Res"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0147-619X(85)90053-8"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"4419","DOI":"10.1016\/S0021-9258(17)34736-1","article-title":"Solubilization and partial purification of yeast chitin synthase, Confirmation of the zymogenic nature of the enzyme","volume":"243","author":"Duran A.","year":"1978","journal-title":"J Biol Chem"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-86-1-115"},{"key":"e_1_2_1_11_1","volume-title":"Candida and Candidiosis. A Review and Bibliography","author":"Odds F.C.","year":"1988"},{"key":"e_1_2_1_12_1","unstructured":"Orlean P.(1982)Polysaccharide synthesis in the dimorphic fungus Candida albicans.Ph.D. Thesis University of Cambridge Cambridge UK ."},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"5732","DOI":"10.1016\/S0021-9258(18)45636-0","article-title":"Two chitin synthases in Saccharomyces cerevisiae","volume":"262","author":"Orlean P.","year":"1987","journal-title":"J Biol Chem"},{"key":"e_1_2_1_14_1","first-page":"93","volume-title":"VIIth International Specialized Symposium on Yeast","author":"Orlean P.a.B.","year":"1981"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5463"},{"key":"e_1_2_1_16_1","volume-title":"Methods in yeast genetics","author":"Sherman F.","year":"1979"}],"container-title":["Molecular Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2958.1992.tb01494.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2958.1992.tb01494.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T08:33:53Z","timestamp":1698050033000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2958.1992.tb01494.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["10.1111\/j.1365-2958.1992.tb01494.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2958.1992.tb01494.x","archive":["Portico"],"relation":{},"ISSN":["0950-382X","1365-2958"],"issn-type":[{"value":"0950-382X","type":"print"},{"value":"1365-2958","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]}}}