{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:54:39Z","timestamp":1761058479707},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,6,29]],"date-time":"2006-06-29T00:00:00Z","timestamp":1151539200000},"content-version":"vor","delay-in-days":11443,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scand J Immunol"],"published-print":{"date-parts":[[1975,3]]},"abstract":"<jats:p>Sterile female homozygous <jats:italic>nude<\/jats:italic> mice were rendered fertile through a graft of thymic epithelium from heterozygous littermates 3 days after birth Homozygous <jats:italic>nude<\/jats:italic> embryos were compared with embryos of comparable age (8\u201018 days). In <jats:italic>nude<\/jats:italic> mice, the embryological anomaly is noticeable from the 11th day of gestation and essentially consists of a failure of the ectoderm from the 3rd branchial cleft to proliferate and differentiate into a cervical vesicle. As a result, the endoderm from the 3rd pouch degenerates into cystic formations instead of differentiating<\/jats:p>","DOI":"10.1111\/j.1365-3083.1975.tb02616.x","type":"journal-article","created":{"date-parts":[[2006,6,30]],"date-time":"2006-06-30T11:37:20Z","timestamp":1151667440000},"page":"193-196","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Nude Mouse Embryo: Ectodermal Nature of the Primordial Thymic Defect"],"prefix":"10.1111","volume":"4","author":[{"given":"A C","family":"CORDIER","sequence":"first","affiliation":[]},{"given":"J F.","family":"HEREMANS","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,6,29]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(60)90009-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5320(74)90024-0"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02118610"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300010168"},{"key":"e_1_2_1_6_2","first-page":"23","volume-title":"Proceedings of the In International Workshop on Nude Mice","author":"Hair J","year":"1974"},{"key":"e_1_2_1_7_2","article-title":"Differentiation of T\u2010cell precursors in nude mice demonstrated by immunofluorescence of T\u2010cell membrane markers","volume":"1044","author":"Loor F.","year":"1973","journal-title":"J Med. 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