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IgD synthesized by lymphocytes and inserted into the cell membrane displayed a single molecular form with the same mobiliiy in sodium dodecyl sulphate polyacrylamide gel eleclrophorcsis (SDS\u2010PAGE) as the previously described slow migrating serum IgDl. Plasma cells produced and secreted IgD1 and another IgD corresponding to the faster\u2010moving serum IgD2. Conversion of one molecular form into the other was never observed, thus indicating that neither molecule is a precursor or a degradation product of the other.<\/jats:p>","DOI":"10.1111\/j.1365-3083.1979.tb01350.x","type":"journal-article","created":{"date-parts":[[2006,6,30]],"date-time":"2006-06-30T14:35:52Z","timestamp":1151678152000},"page":"275-280","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Characterization of IgD"],"prefix":"10.1111","volume":"10","author":[{"given":"G.","family":"CORTE","sequence":"first","affiliation":[]},{"given":"G.","family":"VIALE","sequence":"additional","affiliation":[]},{"given":"E.","family":"COSULICH","sequence":"additional","affiliation":[]},{"given":"A.","family":"BARGELLESI","sequence":"additional","affiliation":[]},{"given":"M.","family":"FERRARINI","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,6,29]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.140.3.742"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830090614"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/252418a0"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1979.tb02716.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(73)80684-2"},{"key":"e_1_2_1_7_2","volume-title":"1978 P. 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Asofsky R.&Paul W.E.Cell membrane IgD: demonstration of IgD on human lymphocytes by enzyme catalized iodination and comparison with cell surface Ig of mouse Submitted for publication."},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830040303"},{"key":"e_1_2_1_14_2","first-page":"179","volume-title":"Methods in Virology","author":"Maizel J.V.","year":"1971"},{"key":"e_1_2_1_15_2","first-page":"409","article-title":"XVI. Polypeptide chain structure of mouse IgM and IgD\u2010likc molecule","volume":"116","author":"Melcher V.","year":"1976","journal-title":"J. Immunol."},{"key":"e_1_2_1_16_2","first-page":"76","article-title":"Synthesis, surface deposition and secretion of immunuglobulin M in bone marrow\u2010derived lymphocytes before and after mitogenic stimulation","volume":"14","author":"Melchers F.","year":"1973","journal-title":"Transplant. 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