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To investigate this question, Fc\u03b3 receptors on effector cells were modulated by interaction with IgG immune complexes. As a consequence of this modulation, T<jats:sub>G<\/jats:sub> cells lost most of their ADCC activity but retained a significant part of their natural killer activity. Thus, these experiments demonstrate that the cytotoxic mechanisms exerted by the same cell population can be dissociated experimentally. Furthermore, they suggest that the net natural cytotoxicity of normal human lymphocytes in certain effector cell\u2010target cell combinations is the result of distinct types of reaction.<\/jats:p>","DOI":"10.1111\/j.1365-3083.1979.tb02734.x","type":"journal-article","created":{"date-parts":[[2006,6,30]],"date-time":"2006-06-30T13:25:53Z","timestamp":1151673953000},"page":"291-296","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Natural Cytotoxicity of Human Fc\u03b3\u2010Receptor\u2010positive T Lymphocytes after Surface Modulation with Immune Complexes"],"prefix":"10.1111","volume":"9","author":[{"given":"G. 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