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By 5\u20106 weeks of age, body and brain weights of asphyxiated rats were no longer significantly different from control animals. However, an increase in brain norepinephrine synthesis was found to persist after maturation. An alteration of serotonin metabolism was found after maturation only in asphyxiated males. The possibility that neonatal asphyxia in the rat is a model for abnormal development of monoamine metabolism, relevant to early childhood behavior disorders such as infantile autism or the syndrome of minimal brain dysfunction, is discussed.<\/jats:p>","DOI":"10.1111\/j.1471-4159.1976.tb06470.x","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T06:15:53Z","timestamp":1160028953000},"page":"893-900","source":"Crossref","is-referenced-by-count":28,"title":["NEONATAL ASPHYXIA IN THE RAT: GREATER VULNERABILITY OF MALES AND PERSISTENT EFFECTS ON BRAIN MONOAMINE SYNTHESIS"],"prefix":"10.1111","volume":"26","author":[{"given":"Nicole","family":"Simon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Volicer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(71)90873-8"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/226371a0"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/92.2.233"},{"key":"e_1_2_1_5_1","first-page":"548","volume":"11","author":"Brodie B. 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