{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T14:07:24Z","timestamp":1761401244293},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,8,12]],"date-time":"2005-08-12T00:00:00Z","timestamp":1123804800000},"content-version":"vor","delay-in-days":4790,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[1992,7]]},"abstract":"<jats:p><jats:bold>Summary: <\/jats:bold> We performed an extended follow\u2010up study assessing the efficacy of stereotactic lesionectomy in 23 patients with foreign\u2010tissue lesions and intractable partial epilepsy. Sixteen lesions involved functional or eloquent cortex as determined by anatomic localization. By definition, the surgical objective in these patients was excision of the lesion, and not the surrounding cerebral cortex. The mean duration of follow\u2010up was 48.5 months (range 26\u201369 months). Seventeen patients (74%) had a significant reduction in seizures (90%) after lesionectomy. Thirteen patients (56%) had a class I operative out\u2010come (seizure\u2010free, single seizure episode, or auras only). Five of these patients were successfully discontinued from antiepileptic drug (AED) therapy. Patients with temporal lobe lesions were statistically less likely to be rendered seizure\u2010free (p &lt; 0.05). Age at operation, duration of epilepsy, and underlying pathology were not significant predictors of seizure outcome. The anatomic distribution of extracranial EEG recorded epileptiform activity did not appear to be an important determinant of outcome. The absence of interictal epileptiform activity in the 3\u2010month postoperative EEG correlated with a significant reduction in seizures. Long\u2010term follow\u2010up indicates that lesionectomy may be effective in select patients with medically refractory partial seizure disorders.<\/jats:p>","DOI":"10.1111\/j.1528-1157.1992.tb02340.x","type":"journal-article","created":{"date-parts":[[2005,8,12]],"date-time":"2005-08-12T10:23:08Z","timestamp":1123842188000},"page":"639-644","source":"Crossref","is-referenced-by-count":141,"title":["Long\u2010Term Follow\u2010Up of Stereotactic Lesionectomy in Partial Epilepsy: Predictive Factors and Electroencephalographic Results"],"prefix":"10.1111","volume":"33","author":[{"given":"Gregory D.","family":"Cascino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank W.","family":"Sharbrough","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph 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