{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:10:08Z","timestamp":1761765008583},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"vor","delay-in-days":8615,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Alcoholism Clin &amp;amp; Exp Res"],"published-print":{"date-parts":[[1984,7]]},"abstract":"<jats:p>The hypothesis was tested that neuropsychological differences exist between males who have an alcoholic parent, sister, or brother (FH+) versus those who do not (FH\u2010). Neuropsychological tests measuring verbal, learning\/memory, abstracting\/problem solving, and perceptual\u2010motor performance were given to four groups of middle\u2010aged subjects: alcoholic FH+ (<jats:italic>n<\/jats:italic>= 41); alcoholic FH\u2010 (<jats:italic>n<\/jats:italic>= 27); nonalcoholic FH+ (<jats:italic>n<\/jats:italic>= 19); and nonalcoholic FH\u2010 (<jats:italic>n<\/jats:italic>= 43). FH+ subjects performed significantly poorer than FH\u2010 subjects on the abstracting\/ problem solving and perceptual\u2010motor tasks, and approached significance on the verbal and teaming\/memory measures. Alcoholics performed more poorly than nonalcoholics on abstracting\/problem solving and learning\/memory tasks. There were no groups by family history significant interactions. From these results we suggest (1) a performance deficit in abstracting\/problem solving and possibly learning\/memory may antedate the alcoholic stage in FH+ individuals; (2) alcoholism and positive famiry history of alcoholism have independent, additive deleterious effects on cognitive\u2010perceptual functioning; and (3) future neuropsychological studies of alcoholism should consider the frequency of FH+ and FH\u2010 individuals in both alcoholic and control groups.<\/jats:p>","DOI":"10.1111\/j.1530-0277.1984.tb05678.x","type":"journal-article","created":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T20:25:49Z","timestamp":1201897549000},"page":"347-351","source":"Crossref","is-referenced-by-count":70,"title":["Neuropsychological Differences between Male Familial and Nonfamilial Alcoholics and Nonalcoholics"],"prefix":"10.1111","volume":"8","author":[{"given":"Kim Walter","family":"Schaeffer","sequence":"first","affiliation":[]},{"given":"Oscar A.","family":"Parsons","sequence":"additional","affiliation":[]},{"given":"J. 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