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Most enzymes of <jats:italic>Giardia<\/jats:italic> core metabolism, however, are related more closely to eubacterial and metazoan homologs. An archaebacterial relationship has been noted previously for the unusual acetyl\u2010CoA synthetase (ADP\u2010forming) of this organism. The results suggest that phosphoenolpyruvate carboxykinase and acetyl\u2010CoA synthetase have been acquired from different sources than most enzymes of <jats:italic>Giardia<\/jats:italic> core metabolism.<\/jats:p>","DOI":"10.1111\/j.1550-7408.2001.tb00184.x","type":"journal-article","created":{"date-parts":[[2005,7,11]],"date-time":"2005-07-11T18:12:46Z","timestamp":1121105566000},"page":"493-497","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Archaebacterial Relationships of the Phosphoenolpyruvate Carboxykinase Gene Reveal Mosaicism of <i>Giardia intestinalis<\/i> Core Metabolism"],"prefix":"10.1111","volume":"48","author":[{"given":"SETSUO","family":"SUGURI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KATRIN","family":"HENZE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LIDYA B.","family":"S\u00c1NCHEZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DOROTHY V.","family":"MOORE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MIKL\u00d3S","family":"M\u00dcLLER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,7,11]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"MOLPHY Version 2.3: Programs for Molecular Phylogenetics Based on Maximum Likelihood. 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