{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,21]],"date-time":"2024-01-21T15:49:51Z","timestamp":1705852191100},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,1,21]],"date-time":"2008-01-21T00:00:00Z","timestamp":1200873600000},"content-version":"vor","delay-in-days":14021,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[1969,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Two girls with Cornelia de Lange Syndrome, dying at the age of 4 weeks and 9 months respectively, are described.<\/jats:p><jats:p>Published examples where necropsy was performed are reviewed and the congenital anomalies of internal organs are summarised.<\/jats:p><jats:p>Although some neuropathological features probably result from arrest or retardation of maturation, there was evidence in the younger infant of associated breakdown of myelin.<\/jats:p><jats:p>Morphological changes of pituitary, thyroid and adrenal glands, are frequent but no link with hypothalamic lesions has been found.<\/jats:p>","DOI":"10.1111\/j.1651-2227.1969.tb04748.x","type":"journal-article","created":{"date-parts":[[2008,1,22]],"date-time":"2008-01-22T00:04:33Z","timestamp":1200960273000},"page":"470-480","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["PATHOLOGICAL FEATURES IN THE DE LANGE SYNDROME"],"prefix":"10.1111","volume":"58","author":[{"given":"N. E.","family":"FRANCE","sequence":"first","affiliation":[]},{"given":"L.","family":"CROME","sequence":"additional","affiliation":[]},{"given":"J. M.","family":"ABRAHAM","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2008,1,21]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1968.tb07302.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1965.tb06370.x"},{"key":"e_1_2_1_4_2","first-page":"236","article-title":"Brachmann\u2010de Lange Syndrome. A report of four cases","volume":"7","author":"Choo P. 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G.","year":"1967","journal-title":"Canad Med Ass J"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(63)80234-6"},{"key":"e_1_2_1_16_2","first-page":"249","article-title":"Drei neue Beobachtungen des Corne\u2010lia\u2010de\u2010Lange Syndroms (Typus Degenerativus Amstelodamensis)","volume":"164","author":"Richter H.","year":"1961","journal-title":"Arch Kinderheilk"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.38.200.349"},{"key":"e_1_2_1_18_2","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1001\/archderm.1966.01600240068011","article-title":"Cutaneous manifestations of the Cornelia de Lange Syndrome","volume":"93","author":"Schuster D. 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