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During the first 3 postoperative months relative weight increased 7gt;10% in 14\/21 children (there was one surgical death). One year after surgery 13\/21 were obese. Neither the size of the tumor nor the mode of surgery was decisive in the development of the obesity. Serum insulin and insulin\u2010like growth factor I (IGF\u2010I) were assessed in four children with growth hormone deficiency (GHD) who, after surgery for craniopharyngioma, were growing normally without GH substitution. One of them was normal in weight and had normal insulin and IGF\u2010I levels; the others were obese and had supranormal insulin and subnormal IGF\u2010I levels. One of the four and two other children with unsubstituted GHD reached final height SDS \u20100.8, \u20102.0 and \u20102.4. One child with normal postoperative GH response reached final height SDS \u20100.7. Final height SDS \u2267\u20102.5 was gained with GH substitution by 6\/11 children. It was &gt;2.0 SD below the height SDS expected from the heights of the parents in 7\/11. An adequate monitoring of children's growth would lead to earlier diagnosis and probably better outcome.<\/jats:p>","DOI":"10.1111\/j.1651-2227.1988.tb10705.x","type":"journal-article","created":{"date-parts":[[2008,1,21]],"date-time":"2008-01-21T19:13:58Z","timestamp":1200942838000},"page":"587-592","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":77,"title":["Children with Craniopharyngioma"],"prefix":"10.1111","volume":"77","author":[{"given":"RITVA","family":"SORVA","sequence":"first","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2008,1,21]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-49-579-206"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01401226"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)33669-0"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198311103091902"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-42-2-370"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-35-1-13"},{"key":"e_1_2_1_8_2","first-page":"311","article-title":"Return of normal growth following removal of a craniopharyngioma","volume":"116","author":"Frasier SD","year":"1968","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1976.tb01984.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(68)80428-7"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(74)80310-0"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00442445"},{"key":"e_1_2_1_13_2","first-page":"465","article-title":"Evaluation of growth in children (in Finnish)","volume":"101","author":"Sorva R","year":"1985","journal-title":"Duodecim"},{"key":"e_1_2_1_14_2","first-page":"32","volume-title":"Growth at adolescence","author":"Tanner JM","year":"1962"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-195909000-00030"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01406660"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.22.6.710"},{"key":"e_1_2_1_18_2","doi-asserted-by":"crossref","unstructured":"SorvaR HeiskanenO PerheentupaJ.Craniopharyngioma in children. 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