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Nevertheless, communication between them and their reciprocal effects on each other constitute an exciting and as\u2010yet unsolved problem in reproductive medicine. Cross\u2010talk among the embryo, endometrium, and the corpus luteum are known to occur in ruminants and primates; more specifically, endometrial\u2010embryonic interactions have been reported in rodents and primates. Here, we present updated information in humans on the embryonic regulation of endometrial epithelial molecules such as chemokines, adhesion molecules, antiadhesion molecules, and leptin during the apposition and adhesion phases of human implantation. Also the embryonic induction of apoptosis in endometrial epithelial cells as a mechanism for crossing the epithelial barrier will be described.<\/jats:p>","DOI":"10.1111\/j.1749-6632.2001.tb03785.x","type":"journal-article","created":{"date-parts":[[2010,7,20]],"date-time":"2010-07-20T20:23:52Z","timestamp":1279657432000},"page":"1-16","source":"Crossref","is-referenced-by-count":44,"title":["Embryo Effects in Human Implantation"],"prefix":"10.1111","volume":"943","author":[{"given":"CARLOS","family":"SIM\u00d3N","sequence":"first","affiliation":[]},{"given":"FRANCISCO","family":"DOMINGUEZ","sequence":"additional","affiliation":[]},{"given":"JOS\u00c9","family":"REMOH\u00cd","sequence":"additional","affiliation":[]},{"given":"ANTONIO","family":"PELLICER","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,1,25]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod54.3.563"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.82.8.2607"},{"key":"e_1_2_7_4_2","first-page":"2638","article-title":"Co\u2010culture of human embryos with autologous human endometrial epithelial cells in patients with repeated implantation failures","volume":"84","author":"Sim\u00f3n C.","year":"1999","journal-title":"J. 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