{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T08:01:16Z","timestamp":1758268876485},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T00:00:00Z","timestamp":1397088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Evolutionary Biology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Reconstructing the ancestral characteristics of species is a major goal in evolutionary and comparative biology. Unfortunately, fossils are not always available and sufficiently informative, and phylogenetic methods based on models of character evolution can be unsatisfactory. Genomic data offer a new opportunity to estimate ancestral character states, through (i) the correlation between DNA evolutionary processes and species life\u2010history traits and (ii) available reliable methods for ancestral sequence inference. Here, we assess the relevance of mitochondrial DNA \u2013 the most popular molecular marker in animals \u2013 as a predictor of ancestral life\u2010history traits in mammals, using the order of Cetartiodactyla as a benchmark. Using the complete set of 13 mitochondrial protein\u2010coding genes, we show that the lineage\u2010specific nonsynonymous over synonymous substitution rate ratio (<jats:styled-content style=\"fixed-case\">dN<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">dS<\/jats:styled-content>) is closely correlated with the species body mass, longevity and age of sexual maturity in Cetartiodactyla and can be used as a marker of ancestral traits provided that the noise introduced by short branches is appropriately dealt with. Based on ancestral <jats:styled-content style=\"fixed-case\">dN<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">dS<\/jats:styled-content> estimates, we predict that the first cetartiodactyls were relatively small animals (around 20\u00a0kg). This finding is in accordance with Cope's rule and the fossil record but could not be recovered via continuous character evolution methods.<\/jats:p>","DOI":"10.1111\/jeb.12361","type":"journal-article","created":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T15:27:14Z","timestamp":1397143634000},"page":"899-910","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Mitochondrial <scp>DNA<\/scp> as a tool for reconstructing past life\u2010history traits in mammals"],"prefix":"10.1093","volume":"27","author":[{"given":"E.","family":"Figuet","sequence":"first","affiliation":[{"name":"UMR 5554, ISEM CNRS Universit\u00e9 Montpellier 2 Montpellier France"}]},{"given":"J.","family":"Romiguier","sequence":"additional","affiliation":[{"name":"UMR 5554, ISEM CNRS Universit\u00e9 Montpellier 2 Montpellier France"}]},{"given":"J. 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