{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T21:33:27Z","timestamp":1775511207960,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T00:00:00Z","timestamp":1356652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2013,3]]},"abstract":"Background<\/jats:title>A group of patients with severe acute respiratory distress syndrome (ARDS<\/jats:styled-content>) is resistant to advanced respiratory therapy. In these patients, extracorporeal membrane oxygenation (ECMO<\/jats:styled-content>) can be used as a rescue therapy. This study presents 14 years of experience from a S<\/jats:styled-content>candinavian ECMO<\/jats:styled-content> centre. The aim of the study is to present outcome results and to investigate whether or not simplified acute physiology score II<\/jats:styled-content> (SAPS\u2010II<\/jats:styled-content>), sequential organ failure assessment (SOFA<\/jats:styled-content>) and\/or M<\/jats:styled-content>urray scores can be used to predict patients' outcome.<\/jats:p><\/jats:sec>Methods<\/jats:title>I<\/jats:styled-content>n a prospective observational study, we collected data from ECMO<\/jats:styled-content> patients from J<\/jats:styled-content>anuary 1997 to M<\/jats:styled-content>arch 2011. The treatment was based mainly on venous\u2010venous ECMO<\/jats:styled-content> and centrifugal pumps. Patients were retrieved from D<\/jats:styled-content>enmark plus a number from S<\/jats:styled-content>weden and N<\/jats:styled-content>orway. The inclusion criteria were the classical criteria until N<\/jats:styled-content>ovember 2009 (n<\/jats:italic>\u2009=\u2009100), after which the new E<\/jats:styled-content>xtracorporeal L<\/jats:styled-content>ife S<\/jats:styled-content>upport O<\/jats:styled-content>rganisation criteria (n<\/jats:italic>\u2009=\u200924) were used.<\/jats:p><\/jats:sec>Results<\/jats:title>One hundred and twenty\u2010four patients were enrolled with median age 45 (range 16\u201367) years. The median M<\/jats:styled-content>urray score was 3.7 (2.5\u20134.0). One hundred and six (85%) of the patients were retrieved from referring hospitals on ECMO<\/jats:styled-content>. The median duration of the ECMO<\/jats:styled-content> runs was 215 (1\u2013578)\u2009h. Ninety\u2010seven (78%) of the patients could be weaned from ECMO<\/jats:styled-content>. A total of 88 (71%) were discharged alive to the referring hospitals. High SAPS\u2010II<\/jats:styled-content>, SOFA<\/jats:styled-content> and M<\/jats:styled-content>urray scores were associated with a high mortality.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Patients with severe ARDS<\/jats:styled-content> have a favourable outcome when treated with ECMO<\/jats:styled-content> and when an ECMO<\/jats:styled-content> retrieval team establishes the ECMO<\/jats:styled-content> treatment at the referring hospital. SAPS\u2010II<\/jats:styled-content>, SOFA<\/jats:styled-content> and M<\/jats:styled-content>urray scores predicted the outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12050","type":"journal-article","created":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T10:21:45Z","timestamp":1356690105000},"page":"303-311","source":"Crossref","is-referenced-by-count":40,"title":["Extracorporeal membrane oxygenation in adult patients with severe acute respiratory failure"],"prefix":"10.1111","volume":"57","author":[{"given":"C.","family":"LINDSKOV","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. H.","family":"JENSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"SPROGOE","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. E.","family":"KLAABORG","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"KIRKEGAARD","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. K","family":"SEVERINSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. G","family":"LORENTSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"FOLKERSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"ILKJAER","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. M.","family":"PEDERSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Aarhus University Hospital Aarhus N Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01704707"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-1976"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005043421801"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181e795ee"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.1.54"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12329-X"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1001\/jama.1979.03300200023016","article-title":"Extracorporeal membrane oxygenation in acute severe respiratory failure. A randomized prospective study","volume":"16","author":"Zapol WM","year":"1979","journal-title":"JAMA"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.2.8306022"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61069-2"},{"key":"e_1_2_7_11_1","first-page":"131","article-title":"Extracorporeal membrane oxygenation (ECMO) reconsidered","volume":"12","author":"Moran JL","year":"2010","journal-title":"Crit Care Resusc"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340050418"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340000697"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(00)00432-3"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00101-004-0653-9"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000141159.90676.2d"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1471"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181f268f1"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318168ea3e"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03510240069035"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01709751"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/138.3.720"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2011.05.009"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0933-3"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.112.3.759"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.14.1754"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e3182238b55"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340101060"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2007.00381.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1051\/ject\/200840123","article-title":"Novoseven use in a non\u2010cardiac pediatric ECMO patient with uncontrolled bleeding","volume":"40","author":"Preston TJ","year":"2008","journal-title":"J Extra Corpor Technol"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2005.03.027"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.02.018"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezr082"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2008.01808.x"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.12050","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.12050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T12:52:10Z","timestamp":1698670330000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.12050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,28]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/aas.12050"],"URL":"https:\/\/doi.org\/10.1111\/aas.12050","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,28]]}}}