{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T23:01:38Z","timestamp":1744758098500},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T00:00:00Z","timestamp":1357171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2013,7]]},"abstract":"Background<\/jats:title>Drug\u2010induced nausea and vomiting, both post\u2010operatively and following chemotherapy, is often distressing for the patients. Our clinical impression is that certain patients are not prone to but instead protected against both post\u2010operative and chemotherapy\u2010induced nausea and vomiting (CINV<\/jats:styled-content>). If support for this hypothesis could be generated, it might be easier to identify such patients as low\u2010risk patients and judge all other patients as high\u2010risk patients by default.<\/jats:p><\/jats:sec>Methods<\/jats:title>All patients scheduled for breast cancer surgery at D<\/jats:styled-content>anderyd H<\/jats:styled-content>ospital, S<\/jats:styled-content>tockholm, S<\/jats:styled-content>weden during 1 year (March 2003\u2013March 2004) were asked to participate in this prospective, observational study. A number of women went on to receive adjuvant chemotherapy. Post\u2010operatively, patients were assessed for 24\u2009h with regard to the occurrence of post\u2010operative nausea and vomiting (PONV<\/jats:styled-content>). CINV<\/jats:styled-content> was assessed for 5 days after start of chemotherapy.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 275 women were included, 33% were classified as PONV<\/jats:styled-content> and 67% as non\u2010PONV<\/jats:styled-content>.<\/jats:p>Sixty\u2010one of the 275 women included were later subjected to adjuvant chemotherapy. In the non\u2010PONV<\/jats:styled-content> group, 95% of the patients did not experience CINV<\/jats:styled-content>, whereas the association between PONV<\/jats:styled-content> and subsequent CINV<\/jats:styled-content> was only 38%.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>A substantially stronger interrelationship was found between non\u2010PONV<\/jats:styled-content> and non\u2010CINV<\/jats:styled-content> than between both PONV<\/jats:styled-content> and CINV<\/jats:styled-content>. This may suggest that certain patients, instead of being prone to nausea and vomiting, in fact in some way are protected against these unpleasant side effects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12053","type":"journal-article","created":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T08:40:07Z","timestamp":1357202407000},"page":"749-753","source":"Crossref","is-referenced-by-count":7,"title":["Is there an association between PONV<\/scp> and chemotherapy\u2010induced nausea and vomiting?"],"prefix":"10.1111","volume":"57","author":[{"given":"E.","family":"ODDBY\u2010MUHRBECK","sequence":"first","affiliation":[{"name":"Division of Anaesthesia and Intensive Care Danderyd Hospital Department of Clinical Sciences Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"\u00d6BRINK","sequence":"additional","affiliation":[{"name":"Division of Anaesthesia and Intensive Care Danderyd Hospital Department of Clinical Sciences Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"EKSBORG","sequence":"additional","affiliation":[{"name":"Childhood Cancer Research Unit Department of Women's and Children's Health Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"ROTSTEIN","sequence":"additional","affiliation":[{"name":"Department of Oncology\u2010Pathology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. 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