{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T23:49:12Z","timestamp":1784159352591,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,2,18]],"date-time":"2013-02-18T00:00:00Z","timestamp":1361145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2013,4]]},"abstract":"Background<\/jats:title>Ultrasound guidance has been shown to reduce the minimum effective volume (MEV<\/jats:styled-content>) of local anaesthetics for several peripheral nerve blocks. Although the lateral sagittal infraclavicular block (LSIB<\/jats:styled-content>) is a well\u2010established anaesthesia method, MEV<\/jats:styled-content> for this technique has not been established. Our aim with this study was to determine the MEV<\/jats:styled-content> using ropivacaine 7.5\u2009mg\/ml for the LSIB<\/jats:styled-content> method.<\/jats:p><\/jats:sec>Methods<\/jats:title>Twenty\u2010five adult American Society of Anesthesiologists physical status I<\/jats:styled-content>\u2010II<\/jats:styled-content> patients scheduled for hand surgery received an ultrasound\u2010guided LSIB<\/jats:styled-content> with ropivacaine 7.5\u2009mg\/ml. A successful block was defined as anaesthesia or analgesia for all five sensory nerves distal to the elbow, 30\u2009min after local anaesthetic injection. The MEV<\/jats:styled-content> for a successful block in 50% of the patients was determined by using the staircase up\u2010and\u2010down method introduced by D<\/jats:styled-content>ixon and M<\/jats:styled-content>assey. Logistic regression and probit transformation were applied to estimate the MEV<\/jats:styled-content> for a successful block in 95% of the patients.<\/jats:p><\/jats:sec>Results<\/jats:title>The patients received ropivacaine 7.5\u2009mg\/ml volumes in the range of 12.5\u201330\u2009ml. The MEVs<\/jats:styled-content> in 50% and 95% of the patients were 19\u2009ml [95% confidence interval (CI<\/jats:styled-content>), 14\u201327] and 31\u2009ml (95% CI<\/jats:styled-content>, 18\u201345), respectively.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>For surgery distal to the elbow, the MEV<\/jats:styled-content> in 95% of patients for an ultrasound\u2010guided LSIB<\/jats:styled-content> with ropivacaine 7.5\u2009mg\/ml was estimated to be 31\u2009ml (95% CI<\/jats:styled-content>, 18\u201345\u2009ml). Further studies should determine the factors that influence the volume of local anaesthetic required for a successful infraclavicular block.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12078","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T13:38:31Z","timestamp":1361281111000},"page":"495-501","source":"Crossref","is-referenced-by-count":19,"title":["Minimum effective volume of ropivacaine 7.5\u2009mg\/ml for an ultrasound\u2010guided infraclavicular brachial plexus block"],"prefix":"10.1111","volume":"57","author":[{"given":"S.","family":"FLOHR\u2010MADSEN","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology University Hospital of North Norway Troms\u00f8 Norway"},{"name":"Institute of Clinical Medicine University of Troms\u00f8 Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. M.","family":"YTREB\u00d8","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology University Hospital of North Norway Troms\u00f8 Norway"},{"name":"Institute of Clinical Medicine University of Troms\u00f8 Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"KREGNES","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology University Hospital of North Norway Troms\u00f8 Norway"},{"name":"Institute of Clinical Medicine University of Troms\u00f8 Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"WILSGAARD","sequence":"additional","affiliation":[{"name":"Department of Community Medicine University of Troms\u00f8 Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d8.","family":"KLAASTAD","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology University Hospital of North Norway Troms\u00f8 Norway"},{"name":"Institute of Clinical Medicine University of Troms\u00f8 Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e31825cb3d6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq306"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e31822b876f"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e3181b49256"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e3181fa1190"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181a915c7"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq050"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2010.06247.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e31819a9542"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e3182289f59"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200601000-00028"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e31820d4266"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00115550-200507000-00003"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e318173280f"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e32832eb7d3"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2009.02206.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000242529.96675.fd"},{"key":"e_1_2_6_19_1","volume-title":"Introduction to statistical analysis","author":"Dixon WJ","year":"1983"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aem100"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31817ef259"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aef186"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.12078","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.12078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T14:23:15Z","timestamp":1697379795000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.12078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,18]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/aas.12078"],"URL":"https:\/\/doi.org\/10.1111\/aas.12078","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,18]]}}}