{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:52:44Z","timestamp":1788555164550,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T00:00:00Z","timestamp":1360022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2013,7]]},"abstract":"Background<\/jats:title>Tracheal intubation may cause vocal fold damage. The trial was designed to assess laryngeal morbidity comparing the E<\/jats:styled-content>ndoflex\u00ae<\/jats:sup> tube with a conventional endotracheal tube with stylet. We hypothesised that laryngeal morbidity within the first 24\u2009h after extubation would be lower with the E<\/jats:styled-content>ndoflex tube than with the conventional endotracheal tube with stylet because of less rigidity.<\/jats:p><\/jats:sec>Methods<\/jats:title>This randomised trial included 130 elective surgical patients scheduled for general anaesthesia with endotracheal intubation. Pre\u2010 and post\u2010operative assessment of hoarseness, vocal fold pathology, and voice analysis using the M<\/jats:styled-content>ultidimensional V<\/jats:styled-content>oice P<\/jats:styled-content>rogram was performed. Induction of anaesthesia was standardised. After complete neuromuscular paralysis, intubation was done with an E<\/jats:styled-content>ndoflex tube or a conventional endotracheal tube with stylet.<\/jats:p><\/jats:sec>Results<\/jats:title>Post\u2010operative hoarseness was found in 45% with the E<\/jats:styled-content>ndoflex tube and 55% with the endotracheal tube with stylet at 24\u2009h after extubation (P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.44). Post\u2010operative vocal fold injury was present in 23% in the E<\/jats:styled-content>ndoflex tube group and in 36% in the endotracheal tube with stylet group (P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.13). The increase in shimmer, the voice analysis variable reflecting vocal fold oedema, was 0.5% in the E<\/jats:styled-content>ndoflex tube group and 2.5% in the endotracheal tube with stylet group (P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>No significant difference was found in the incidence of hoarseness or vocal fold injury using the E<\/jats:styled-content>ndoflex tube. However, the statistically significant lower increase in the shimmer values in that group implies that the E<\/jats:styled-content>ndoflex may be associated with less laryngeal morbidity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12079","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T06:31:19Z","timestamp":1360045879000},"page":"737-744","source":"Crossref","is-referenced-by-count":18,"title":["Laryngeal morbidity after tracheal intubation: the E<\/scp>ndoflex\u00ae<\/sup> tube compared to conventional endotracheal intubation with stylet"],"prefix":"10.1111","volume":"57","author":[{"given":"M. K.","family":"S\u00d8RENSEN","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, Centre of Head and Orthopaedics Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"RASMUSSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Centre of Head and Orthopaedics Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. S.","family":"KRISTENSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Centre of Head and Orthopaedics Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"B\u00d8TTGER","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Centre of Head and Orthopaedics Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. B.","family":"FREDENSBORG","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Centre of Head and Orthopaedics Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. M.","family":"HANSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Centre of Head and Orthopaedics Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. S.","family":"RASMUSSEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Centre of Head and Orthopaedics Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200305000-00005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03017741"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03014336"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03011741"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9924(03)00016-9"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2007.01352.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199712000-00005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199709000-00017"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198709000-00025"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.7.827"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100103433"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1992.tb02121.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/73.6.786"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200609000-00009"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000181290.37527.CE"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61892-3"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2010.09.019"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.12079","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.12079","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T03:52:29Z","timestamp":1700625149000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.12079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,5]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1111\/aas.12079"],"URL":"https:\/\/doi.org\/10.1111\/aas.12079","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,5]]}}}