{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:12:23Z","timestamp":1787497943364,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,4,3]],"date-time":"2013-04-03T00:00:00Z","timestamp":1364947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2013,7]]},"abstract":"\n Background<\/jats:title>\n \n To determine the volumes required for stable haemodynamics and possible effects on the coagulation, we studied stroke volume (\n SV<\/jats:styled-content>\n )\u2010directed administration of hydroxyethyl starch (\n HES<\/jats:styled-content>\n 130\u2009k\n D<\/jats:styled-content>\n a\/0.4) and Ringer's acetate (\n RAC<\/jats:styled-content>\n ) in neurosurgical patients operated on in a sitting position.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Thirty craniotomy patients were randomised to receive either\n HES<\/jats:styled-content>\n or\n RAC<\/jats:styled-content>\n . Before positioning,\n SV<\/jats:styled-content>\n , measured by arterial pressure waveform analysis, was maximised by boluses of fluid until\n SV<\/jats:styled-content>\n did not increase more than 10%.\n SV<\/jats:styled-content>\n was maintained by repeated administration of fluid.\n RAC<\/jats:styled-content>\n 3\u2009ml\/kg\/h was infused in both groups during surgery.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Comparable haemodynamics were achieved with the mean [standard deviation (\n SD<\/jats:styled-content>\n )] cumulative doses of\n HES<\/jats:styled-content>\n or\n RAC<\/jats:styled-content>\n 271 (47) or 264 (50) ml (\n P<\/jats:italic>\n \u2009=\u20090.699) before the sitting position. Mean (\n SD<\/jats:styled-content>\n ) doses of\n HES<\/jats:styled-content>\n or\n RAC<\/jats:styled-content>\n at 30\u2009min after the positioning were 343 (94) or 450 (156) ml (\n P<\/jats:italic>\n \u2009=\u20090.036), and at the end of surgery 464 (284) or 707 (425) ml, respectively (\n P<\/jats:italic>\n \u2009=\u20090.087). The intraoperative fluid balance was more positive in the\n RAC<\/jats:styled-content>\n than in the\n HES<\/jats:styled-content>\n group [\n P<\/jats:italic>\n \u2009=\u20090.044, 95% confidence interval (\n CI<\/jats:styled-content>\n ) \u2212978 to \u221214]. Cardiac and stroke volume indexes [\n CI<\/jats:styled-content>\n and stroke volume index (\n SVI<\/jats:styled-content>\n )] increased in the\n HES<\/jats:styled-content>\n group (\n P<\/jats:italic>\n \u2009<\u20090.05) but not in the\n RAC<\/jats:styled-content>\n group [non significant (N.S.)]. Neither coagulation profile nor blood loss differed between the groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Fluid filling with\n HES<\/jats:styled-content>\n boluses resulted in a positive response in\n CI<\/jats:styled-content>\n and\n SVI<\/jats:styled-content>\n during the sitting position. The 34% smaller volume of\n HES<\/jats:styled-content>\n than crystalloid and less positive fluid balance in the\n HES<\/jats:styled-content>\n group might be important in craniotomy patients with decreased brain compliance.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/aas.12105","type":"journal-article","created":{"date-parts":[[2013,4,3]],"date-time":"2013-04-03T02:56:56Z","timestamp":1364957816000},"page":"729-736","source":"Crossref","is-referenced-by-count":41,"title":["Stroke volume\u2010directed administration of hydroxyethyl starch or\n R<\/scp>\n inger's acetate in sitting position during craniotomy"],"prefix":"10.1111","volume":"57","author":[{"given":"A.\u2010C. B.","family":"LINDROOS","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Central Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"NIIYA","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Sapporo Medical University School of Medicine Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"SILVASTI\u2010LUNDELL","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Central Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"RANDELL","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Central Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"HERNESNIEMI","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Helsinki University Central Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. T.","family":"NIEMI","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Central Hospital Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198807000-00008"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198511000-00001"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198602000-00007"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bja.a013439"},{"key":"e_1_2_6_6_1","first-page":"495","article-title":"Neurosurgical anaesthesia in the sitting position. 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