{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:35:35Z","timestamp":1768437335276,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,9,23]],"date-time":"2014-09-23T00:00:00Z","timestamp":1411430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:p>Pulmonary embolism remains an important clinical problem with a high mortality rate. The potential for sudden and fatal hemodynamic deterioration highlights the need for a prompt diagnosis and appropriate intervention. The purpose of the present case report is to describe a successful peri\u2010operative veno\u2010arterial extra corporeal membrane oxygenation (<jats:styled-content style=\"fixed-case\">VA\u2010ECMO<\/jats:styled-content>) implantation for assumed massive pulmonary embolism associated with high hemodynamic instability and severe hypoxemia. A 52\u2010year\u2010old female victim of a motorcycle accident had been operated on for unstable fractures that required optimal repair. Despite subcutaneous administration of 40\u2009mg enoxaparin on day 0 and day 1, the patient developed a massive pulmonary embolism leading to peri\u2010operative pulseless activity. As intravenous thrombolysis was strictly contraindicated, a <jats:styled-content style=\"fixed-case\">VA\u2010ECMO<\/jats:styled-content> was successfully implanted and permitted to stabilize the patient's hemodynamics. The hemodynamic and respiratory status improved by day 3, and the <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> was removed. A vena cava filter was implanted before successful and definitive stabilization of the femoral fracture and the L2 fracture on days 4 and 5. The patient was able to be mobilized 2 days after the surgery and was transferred to a rehabilitation ward on day 15. At that time, her cognitive functions had fully recovered. <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> can provide lifesaving hemodynamic and respiratory support in patients with massive pulmonary embolism who are too unstable to tolerate other interventions, who have failed other therapies or for whom other therapies are contraindicated.<\/jats:p>","DOI":"10.1111\/aas.12411","type":"journal-article","created":{"date-parts":[[2014,9,23]],"date-time":"2014-09-23T07:47:43Z","timestamp":1411458463000},"page":"1280-1286","source":"Crossref","is-referenced-by-count":28,"title":["Peri\u2010operative massive pulmonary embolism management: is veno\u2010arterial <scp>ECMO<\/scp> a therapeutic option?"],"prefix":"10.1111","volume":"58","author":[{"given":"G.","family":"PAVLOVIC","sequence":"first","affiliation":[{"name":"Division of Anesthesiology Geneva University Hospitals  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"BANFI","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Geneva University Hospitals  Geneva Switzerland"},{"name":"Faculty of Medicine University of Geneva  Geneva Switzerland"},{"name":"Geneva Hemodynamic Research Group  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"TASSAUX","sequence":"additional","affiliation":[{"name":"Intensive Care Service Geneva University Hospitals  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. E.","family":"PETER","sequence":"additional","affiliation":[{"name":"Division of Orthopedic Surgery Geneva University Hospitals  Geneva Switzerland"},{"name":"Faculty of Medicine University of Geneva  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. J.","family":"LICKER","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology Geneva University Hospitals  Geneva Switzerland"},{"name":"Faculty of Medicine University of Geneva  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"BENDJELID","sequence":"additional","affiliation":[{"name":"Intensive Care Service Geneva University Hospitals  Geneva Switzerland"},{"name":"Faculty of Medicine University of Geneva  Geneva Switzerland"},{"name":"Geneva Hemodynamic Research Group  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"GIRAUD","sequence":"additional","affiliation":[{"name":"Intensive Care Service Geneva University Hospitals  Geneva Switzerland"},{"name":"Faculty of Medicine University of Geneva  Geneva Switzerland"},{"name":"Geneva Hemodynamic Research Group  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200111000-00027"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.10.1529"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1302\/0301-620X.77B3.7744936","article-title":"Medullary lavage reduces embolic phenomena and cardiopulmonary changes during cemented hemiarthroplasty","volume":"77","author":"Christie J","year":"1995","journal-title":"J Bone Joint Surg Br"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199412153312401"},{"key":"e_1_2_6_6_1","first-page":"303","article-title":"Post\u2010traumatic fat embolism in the inferior vena cava","volume":"41","author":"Liu P","year":"1990","journal-title":"Can Assoc Radiol J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2009.06.010"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.08.046"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2301"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.971069"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs104"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn310"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e318031cd0c"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.11.1245"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0782"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-200207000-00032"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.3.877"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-135-2-200107170-00010"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-3-200602070-00004"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2044.2001.01724.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309233291305"},{"key":"e_1_2_6_22_1","first-page":"173","article-title":"The significance and pathology of fat embolism","volume":"9","author":"Sevitt S","year":"1977","journal-title":"Ann Clin Res"},{"key":"e_1_2_6_23_1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/01.NURSE.0000395312.91409.7f","article-title":"Fat embolism syndrome","volume":"41","author":"Carlson DS","year":"2011","journal-title":"Nursing"},{"key":"e_1_2_6_24_1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.4103\/0971-9784.37908","article-title":"Perioperative transoesophageal echocardiography in noncardiac surgery","volume":"9","author":"Bilotta F","year":"2006","journal-title":"Ann Card Anaesth"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201404-0630CP"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.12411","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.12411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:02:18Z","timestamp":1696377738000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.12411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,23]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/aas.12411"],"URL":"https:\/\/doi.org\/10.1111\/aas.12411","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,23]]}}}