{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T18:29:14Z","timestamp":1776450554581,"version":"3.51.2"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T00:00:00Z","timestamp":1426636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2015,4]]},"abstract":"Background<\/jats:title>Multiple studies suggest that transversus abdominis plane (TAP<\/jats:styled-content>) block (without intrathecal morphine) after C<\/jats:styled-content>aesarean section (CS<\/jats:styled-content>) reduces post\u2010operative morphine consumption. In our study, we wanted to compare the analgesic effect of TAP<\/jats:styled-content> block with infiltration of the wound after CS<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>We included 60 pregnant women scheduled for elective CS<\/jats:styled-content> under spinal anaesthesia in a randomised, single\u2010centre, double\u2010blind study. Thirty patients received ultrasound\u2010guided TAP<\/jats:styled-content> block using 20\u2009ml bupivacaine 0.25% with adrenaline 5\u2009\u03bcg\/ml bilaterally and 20\u2009ml normal saline as wound infiltration (TAP<\/jats:styled-content> group). The other 30 patients (the control group) received normal saline 20\u2009ml bilaterally in the TAP<\/jats:styled-content>, and 20\u2009ml bupivacaine 0.25% with adrenaline 5\u2009\u03bcg\/ml as wound infiltration. The main outcome was cumulative morphine consumption at 48\u2009h after surgery. In addition, continuous morphine consumption, pain scores and side effects were registered.<\/jats:p><\/jats:sec>Results<\/jats:title>Fifty\u2010seven patients completed the study. Cumulative morphine consumption at 48\u2009h (mean\u2009\u00b1\u2009standard deviation) was 41\u2009\u00b1\u200934\u2009mg in the TAP<\/jats:styled-content> group and 38\u2009\u00b1\u200927\u2009mg in the control group (P<\/jats:italic>\u2009=\u20090.7); a difference of 3\u2009mg (95% confidence interval \u221213 to 19\u2009mg). Morphine consumption at any time up to 48\u2009h was virtually identical in both groups. Side effects were similar, except for a higher degree of sedation in the TAP<\/jats:styled-content> group (P<\/jats:italic>\u2009=\u20090.04).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Compared with wound infiltration with local anaesthetics, TAP<\/jats:styled-content> block did not reduce cumulative morphine consumption following CS<\/jats:styled-content>. The TAP<\/jats:styled-content> block was associated with more pronounced sedation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12498","type":"journal-article","created":{"date-parts":[[2015,3,19]],"date-time":"2015-03-19T04:54:42Z","timestamp":1426740882000},"page":"496-504","source":"Crossref","is-referenced-by-count":47,"title":["Transversus abdominis plane block vs. wound infiltration in C<\/scp>aesarean section: a randomised controlled trial"],"prefix":"10.1111","volume":"59","author":[{"given":"A.","family":"TELNES","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care St Olav's University Hospital Trondheim Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"SKOGVOLL","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care St Olav's University Hospital Trondheim Norway"},{"name":"Department of Circulation and Medical Imaging Norwegian University of Science and Technology (NTNU) Trondheim Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"LONN\u00c9E","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care St Olav's University Hospital Trondheim Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,18]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"147","article-title":"Post\u2010cesarean section analgesia","volume":"63","author":"Verstraete S","year":"2012","journal-title":"Acta Anaesthesiol Belg"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tacc.2012.01.009"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2012.02.007"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000290294.64090.f3"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep235"},{"key":"e_1_2_7_7_1","first-page":"821","article-title":"Efficacy of 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