{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:19:12Z","timestamp":1773850752890,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,5,31]],"date-time":"2015-05-31T00:00:00Z","timestamp":1433030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Transversus abdominis plane (<jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content>) block is widely used as a part of pain management after various abdominal surgeries. We evaluated the effect of <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content> block as an add\u2010on to the routine analgesic regimen in patients undergoing robot\u2010assisted laparoscopic hysterectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a prospective blinded study, 70 patients scheduled for elective robot\u2010assisted laparoscopic hysterectomy were randomised to receive either <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content> block (ropivacaine 0.5%, 20\u00a0ml on each side) or sham block (isotonic saline 0.9%, 20\u00a0ml on each side). All patients had patient\u2010controlled analgesia (<jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content>) with morphine on top of paracetamol and ibuprofen or diclofenac. For the first 24 post\u2010operative hours, we monitored <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> morphine consumption and pain scores with visual analogue scale (<jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>) at rest and while coughing. Post\u2010operative nausea and number of vomits (<jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content>) were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010five patients completed the study, 34 receiving <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content> block with ropivacaine and 31 receiving sham block with isotonic saline. We found no differences in median (interquartile range) morphine consumption the first 24\u00a0h between the <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content> block group [17.5\u00a0mg (6.9\u201336.0\u00a0mg)] and the placebo group [17.5\u00a0mg (2.9\u201338.0\u00a0mg)] (95% confidence interval 10.0\u201322.6\u00a0mg<jats:italic>, P<\/jats:italic>\u00a0=\u00a00.648). No differences were found for <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> scores between the two groups, calculated as area under the curve\/1\u201324\u00a0h, neither at rest (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.112) nor while coughing (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.345), or for <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content> between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In our study, the <jats:styled-content style=\"fixed-case\">TAP<\/jats:styled-content> block combined with paracetamol and <jats:styled-content style=\"fixed-case\">Nonsteroidal anti\u2010inflammatory drugs (NSAID)<\/jats:styled-content> treatment, had no effect on morphine consumption, <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> pain scores, or frequency of nausea and vomiting after robot\u2010assisted laparoscopic hysterectomy compared with paracetamol and <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content> alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12516","type":"journal-article","created":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T05:17:13Z","timestamp":1433135833000},"page":"928-935","source":"Crossref","is-referenced-by-count":37,"title":["Transversus abdominis plane (<scp>TAP<\/scp>) block after robot\u2010assisted laparoscopic hysterectomy: a randomised clinical trial"],"prefix":"10.1111","volume":"59","author":[{"given":"H.","family":"Torup","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology Herlev University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"B\u00f8geskov","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Herlev University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. G.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Herlev University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Palle","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Herlev University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Surgery Herlev University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. U.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Herlev University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. L.","family":"Petersen","sequence":"additional","affiliation":[{"name":"Section\u00a0of Acute Pain Management Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Mathiesen","sequence":"additional","affiliation":[{"name":"Section\u00a0of Acute Pain Management Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. B.","family":"Dahl","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Copenhagen University Hospital  Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Herlev University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2011.08.008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2681-z"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e3182429531"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.03104.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-012-9729-1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2010.02215.x"},{"issue":"12","key":"e_1_2_7_8_1","first-page":"CD007705","article-title":"Perioperative transversus abdominis plane (TAP)\u00a0blocks for analgesia after abdominal surgery","author":"Charlton S","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.09.012"},{"issue":"419","key":"e_1_2_7_10_1","first-page":"e1","article-title":"Randomized trial of transversus abdominis plane block at total laparoscopic hysterectomy: effect of regional analgesia on quality of recovery","volume":"207","author":"Kane SM","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318236f67f"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2011.01369.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12351"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-11-32"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318265b61a"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2010.00402.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200506000-00027"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.04.026"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2013.03.012"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen103"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000066"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/1658-354X.101213"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000104582.71710.EE"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e328350b0d5"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aet015"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.12516","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.12516","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T20:46:34Z","timestamp":1695501994000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.12516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,31]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/aas.12516"],"URL":"https:\/\/doi.org\/10.1111\/aas.12516","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,31]]}}}