{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T06:29:03Z","timestamp":1776580143448,"version":"3.51.2"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T00:00:00Z","timestamp":1433376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Postoperative nausea and vomiting (<jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content>) remains a problem in the postoperative period. Previous <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content> in oncology patients has recently been associated with chemotherapy\u2010induced nausea and vomiting (<jats:styled-content style=\"fixed-case\">CINV<\/jats:styled-content>). We assessed if <jats:styled-content style=\"fixed-case\">CINV<\/jats:styled-content> could improve Apfel's heuristic for predicting <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective study of 1500 consecutive patients undergoing intermediate or major cancer surgery between April and July 2011. <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content> was assessed in the first postoperative day during post\u2010anaesthesia care. The assigned anaesthetist completed an electronic medical record with all of the studied variables. Multiple logistic regression analyses were performed to assess whether any of the variables could add predictive ability to Apfel's tallying heuristic, and receiver operating characteristic (<jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>) curves were modelled. The areas under the curve (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>) were used to compare the model's discriminating ability for predicting patients who vomited from those who did not vomit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall incidence of <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content> was 26%. Multiple logistic regressions identified two independent predictors for <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content> (odds ratio; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>), Apfel's score (1.78; 1.23\u20132.63) and previous chemotherapy\u2010induced vomiting (3.15; 1.71\u20135.9), Hosmer\u2013Lemeshow's <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001. Previous <jats:styled-content style=\"fixed-case\">CINV<\/jats:styled-content> was the most significant predictor to be added to Apfel's heuristic in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A history of chemotherapy\u2010induced nausea vomiting was a strong predictor for <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content> and should be investigated as an added risk factor for <jats:styled-content style=\"fixed-case\">PONV<\/jats:styled-content> in the preoperative period of oncology surgery in prospective studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12552","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T15:27:41Z","timestamp":1433431661000},"page":"1145-1153","source":"Crossref","is-referenced-by-count":21,"title":["Does previous chemotherapy\u2010induced nausea and vomiting predict postoperative nausea and vomiting?"],"prefix":"10.1111","volume":"59","author":[{"given":"H. B. G.","family":"da Silva","sequence":"first","affiliation":[{"name":"Department of Anaesthesia Cancer Institute of the State of Sao Paulo Pain Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Cancer Institute of the State of Sao Paulo Pain Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. M. N.","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Cancer Institute of the State of Sao Paulo Pain Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Slullitel","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Cancer Institute of the State of Sao Paulo Pain Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. A.","family":"Ashmawi","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Cancer Institute of the State of Sao Paulo Pain Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-012-1468-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199907000-00018"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199909000-00022"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1997.117-az0113.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/88.5.659"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318267ef31"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aet284"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aes276"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000002"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032196"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31817b842c"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-6576.2000.440422.x"},{"key":"e_1_2_8_14_1","first-page":"1132","article-title":"Prediction of postoperative nausea and vomiting using an artificial neural network","volume":"52","author":"Traeger M","year":"2003","journal-title":"Anaesthesist"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/ael282"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0706547"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.12053"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-77"},{"key":"e_1_2_8_19_1","first-page":"225","volume-title":"The Sage Handbook of Social Science Methodology","author":"Dunning T","year":"2007"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-120709-145346"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03020521"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.10.037"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1725-10.2010"},{"key":"e_1_2_8_25_1","doi-asserted-by":"crossref","unstructured":"RoscoeJA MorrowGR AaproMS MolassiotisA OlverI.Anticipatory nausea and vomiting.Support Care Cancer2011;19:1533\u20138.","DOI":"10.1007\/s00520-010-0980-0"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036646"},{"key":"e_1_2_8_27_1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1097\/ACO.0b013e32835956d8","article-title":"Nausea and vomiting after surgery: it is not just postoperative","volume":"25","author":"Lichtor JL","year":"2012","journal-title":"Curr Opin Anaesthesiol"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.12552","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.12552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T12:43:20Z","timestamp":1696509800000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.12552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,4]]},"references-count":26,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/aas.12552"],"URL":"https:\/\/doi.org\/10.1111\/aas.12552","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,4]]}}}