{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T23:05:20Z","timestamp":1778799920603,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,8,2]],"date-time":"2017-08-02T00:00:00Z","timestamp":1501632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006388","name":"H\u00f4pitaux Universitaires de Gen\u00e8ve","doi-asserted-by":"publisher","award":["09\u2010022"],"award-info":[{"award-number":["09\u2010022"]}],"id":[{"id":"10.13039\/501100006388","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Post\u2010partum lower extremity motor and sensory dysfunctions occur in 0.1\u20139.2\u2030 of deliveries. While macrosomia, lithotomy position and forceps use are well\u2010identified causes of peripheral nerve injuries, additional contributors such as patient condition and anaesthesia care may also have to be considered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a case\u2013control study nested in a cohort of 19,840 patients having neuraxial anaesthesia for childbirth. Cases were all patients who developed motor or sensory dysfunction of lower extremities in the post\u2010partum period. These were compared, using Chi\u2010square, Fisher's exact test, logistic regression and time series, to a random sample of controls without any neurological symptoms or injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 19 (0.96\u2030) patients with peripheral nerve injuries of which 15 (0.76\u2030) were likely associated with obstetrical care. In four additional cases (0.20\u2030), a nerve root injury due to the Tuohy needle was suspected. Univariate risk factors were: a gestational age \u2265\u00a041\u00a0weeks, Odds Ratio (OR) 3.8; 95% CI: 1.1\u201313.1, late initiation of neuraxial anaesthesia OR 8.2; 95% CI: 1.8\u201337.9, a repeated anaesthetic procedure OR 2.8; 95% CI: 1.0\u20137.8, assisted delivery with forceps OR 9.8; 95% CI: 1.2\u2013114.1 and newborn birth weight &gt;\u00a03.5\u00a0kg with an OR 6.8; 95% CI: 2.0\u201322.5.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Obstetrical related factors are the most prominent risk associated with peripheral nerve injuries. This study highlights however that patient and anaesthesia\u2010related factors may also contribute to peripheral nerve injuries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.12951","type":"journal-article","created":{"date-parts":[[2017,8,2]],"date-time":"2017-08-02T09:45:39Z","timestamp":1501667139000},"page":"1203-1214","source":"Crossref","is-referenced-by-count":20,"title":["Risk factors for peripheral nerve injuries following neuraxial labour analgesia: a nested case\u2013control study"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7367-7029","authenticated-orcid":false,"given":"G.","family":"Haller","sequence":"first","affiliation":[{"name":"Division of Anaesthesia Department of Anaesthesiology, Pharmacology and Intensive Care Geneva University Hospitals Geneva Switzerland"},{"name":"Department of Epidemiology &amp; Preventive Medicine Health Services Management and Research Unit The Alfred Centre Monash University Melbourne Vic. 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