{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:16:47Z","timestamp":1792189007106,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T00:00:00Z","timestamp":1530489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008363","name":"Kr\u00e6ftens Bek\u00e6mpelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Millions of patients undergo major abdominal surgery worldwide each year, and the post\u2010operative phase carries a high risk of respiratory and circulatory complications. Standard ward observation of patients includes vital sign registration at regular intervals. Patients may deteriorate between measurements, and this may be detected by continuous monitoring. The aim of this study was to compare the number of micro events detected by continuous monitoring to those documented by the widely used standardized Early Warning Score (<jats:styled-content style=\"fixed-case\">EWS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty patients were continuously monitored with peripheral arterial oxygen saturation (SpO<jats:sub>2<\/jats:sub>), heart rate (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>), and respiratory rate (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>) the first 4 days after major abdominal cancer surgery. <jats:styled-content style=\"fixed-case\">EWS<\/jats:styled-content> was monitored as routine practice. Number and duration of events were analyzed using Fisher's exact test and Wilcoxon rank sum test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Continuous monitoring detected a SpO<jats:sub>2<\/jats:sub> &lt;92% in 98% of patients vs 16% of patients detected by <jats:styled-content style=\"fixed-case\">EWS<\/jats:styled-content> (<jats:italic>P<\/jats:italic> &lt; .0001). Micro events of SpO<jats:sub>2<\/jats:sub> &lt;92% lasting longer than 60 minutes were found in 58% of patients by continuous monitoring vs 16% by the <jats:styled-content style=\"fixed-case\">EWS<\/jats:styled-content> (<jats:italic>P<\/jats:italic> &lt; .0001). Fifty\u2010two percent of patients had micro events of SpO<jats:sub>2<\/jats:sub> &lt;85% lasting longer than 10 minutes. Continuous monitoring found tachycardia in 60% of patients vs 6% by the <jats:styled-content style=\"fixed-case\">EWS<\/jats:styled-content>. Frequency of events for bradycardia, tachypnea, and bradypnea showed similar patterns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Very low SpO<jats:sub>2<\/jats:sub> and tachycardia in post\u2010operative patients are common and under\u2010diagnosed by the EWS. Continuous monitoring can discover these micro events and potentially contribute to earlier detection and, potentially, result in prevention of clinical complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13173","type":"journal-article","created":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T10:28:24Z","timestamp":1530527304000},"page":"1200-1208","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Continuous vital sign monitoring after major abdominal surgery\u2014Quantification of micro events"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9893-5573","authenticated-orcid":false,"given":"C. L.","family":"Duus","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Bispebjerg and Frederiksberg Hospital, University of Copenhagen Copenhagen Denmark"},{"name":"Department of Anaesthesiology The Abdominal Centre Rigshospitalet, University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7131-2461","authenticated-orcid":false,"given":"E. K.","family":"Aasvang","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology The Abdominal Centre Rigshospitalet, University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Olsen","sequence":"additional","affiliation":[{"name":"Biomedical Engineering, Department of Electrical Engineering Technical University of Denmark Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. B. D.","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Biomedical Engineering, Department of Electrical Engineering Technical University of Denmark Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7465-5374","authenticated-orcid":false,"given":"L. N.","family":"J\u00f8rgensen","sequence":"additional","affiliation":[{"name":"Digestive Disease Center Bispebjerg and Frederiksberg Hospital, University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. P.","family":"Achiam","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology The Abdominal Centre, Rigshospitalet, University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4885-4609","authenticated-orcid":false,"given":"C. S.","family":"Meyhoff","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Bispebjerg and Frederiksberg Hospital, University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(15)70087-2"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2015.10.001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-4310-5"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000312"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.4360"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2015.03.236"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31821d4a43"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-014-3597-4"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2016.02.003"},{"key":"e_1_2_9_11_1","volume-title":"National Early Warning Score (NEWS): Standardising the Assessment of Acute Illness Severity in the NHS","author":"Royal College of Physicians","year":"2012"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181ca7a9b"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0181448"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2017.09.031"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(94)00001-K"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.5.1694"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000836"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aex140"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.7208"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000049"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002002"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeh208"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeu380"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182652a51"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.04.104"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aex128"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2014.08.037"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/94.10.521"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.13173","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.13173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T14:25:58Z","timestamp":1694787958000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.13173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,2]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1111\/aas.13173"],"URL":"https:\/\/doi.org\/10.1111\/aas.13173","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,2]]},"assertion":[{"value":"2017-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}