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Therefore, a minimal continuous cuff pressure must be maintained. Aim of this study was to analyse the course of cuff pressure in an in\u2010vitro model during manual cuff pressure control manoeuvres.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An artificial trachea was intubated with an appropriately sized <jats:styled-content style=\"fixed-case\">ETT<\/jats:styled-content> and cuff pressure set to 20 cm H<jats:sub>2<\/jats:sub>O. Thirty\u2010two experienced <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> nurses each performed six cuff pressure control manoeuvres (three times in two different <jats:styled-content style=\"fixed-case\">ETT<\/jats:styled-content>s) using a manual cuff pressure manometer. Course of cuff pressure from connecting the manometer to disconnecting it from the cuff pilot balloon was recorded using a pressure transducer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 190 cuff pressure control manoeuvres suitable for analysis. In all control manoeuvres a cuff pressure below 20 cm H<jats:sub>2<\/jats:sub>O was noted. In 20.0% of the control manoeuvres the cuff pressure dropped below 10 cm H<jats:sub>2<\/jats:sub>O. Cuff pressure drops were mainly caused by initially connecting the manometer to the pilot balloon, less frequently by manipulating the pressure gauge of the manometer. Disconnecting the manometer after the control manoeuvre caused a cuff pressure drop in 78.1% of cases, contributing to a final cuff pressure below 20 cm H<jats:sub>2<\/jats:sub>O in 31.3% of control manoeuvres.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Routine manual cuff pressure control manoeuvres in <jats:styled-content style=\"fixed-case\">ETT<\/jats:styled-content> cuffs result in considerable cuff pressure drops. This may have an impact on silent aspiration of pharyngeal contents passing along the cuff into the lower airway.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13249","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T16:20:23Z","timestamp":1534954823000},"page":"55-60","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Endotracheal tube cuff pressure changes during manual cuff pressure control manoeuvres: An in\u2010vitro assessment"],"prefix":"10.1111","volume":"63","author":[{"given":"Norbert","family":"Aeppli","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Kantonsspital Frauenfeld Frauenfeld Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastian","family":"Lindauer","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Kantonsspital Frauenfeld 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