{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:27:08Z","timestamp":1790803628904,"version":"4.1.0"},"reference-count":67,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T00:00:00Z","timestamp":1547510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Rhabdomyolysis\u2010induced acute kidney injury (AKI) is a common and serious condition. We aimed to summarise the available evidence on this topic and provide recommendations according to current standards for trustworthy guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This guideline was developed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE). The following preventive interventions were assessed: (a) fluids, (b) diuretics, (c) alkalinisation, (d) antioxidants, and (e) renal replacement therapy. Exclusively patient\u2010important outcomes were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We suggest using early rather than late fluid resuscitation (weak recommendation, very low quality of evidence). We suggest using crystalloids rather than colloids (weak recommendation, low quality of evidence). We suggest against routine use of loop diuretics as compared to none (weak recommendation, very low quality of evidence). We suggest against use of mannitol as compared to none (weak recommendation, very low quality of evidence). We suggest against routine use of any diuretic as compared to none (weak recommendation, very low quality of evidence). We suggest against routine use of alkalinisation with sodium bicarbonate as compared to none (weak recommendation, low quality of evidence). We suggest against the routine use of any alkalinisation as compared to none (weak recommendation, low quality of evidence). We suggest against routine use of renal replacement therapy as compared to none (weak recommendation, low quality of evidence). For the remaining PICO questions, no recommendations were issued.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The quantity and quality of evidence supporting preventive interventions for rhabdomyolysis\u2010induced AKI is low\/very low. We were able to issue eight weak recommendations and no strong recommendations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13308","type":"journal-article","created":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T09:19:33Z","timestamp":1547543973000},"page":"576-586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["Prevention of rhabdomyolysis\u2010induced acute kidney injury \u2013 A DASAIM\/DSIT clinical practice guideline"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1244-6072","authenticated-orcid":false,"given":"Jens","family":"Michelsen","sequence":"first","affiliation":[{"name":"Department of Intensive Care Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joakim","family":"Cordtz","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University Hospital Zealand  K\u00f8ge Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisbeth","family":"Liboriussen","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, Department for Anesthesiology Regional Hospital Central Jutland  Viborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meike T.","family":"Behzadi","sequence":"additional","affiliation":[{"name":"Cardiothoracic Intensive Care Unit, Department for Anesthesiology Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ibsen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Nordsj\u00e6llands Hospital, University of Copenhagen  Hiller\u00f8d Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette B.","family":"Damholt","sequence":"additional","affiliation":[{"name":"Department of Nephrology 2132 Copenhagen University Hospital  Rigshospitalet Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6378-9673","authenticated-orcid":false,"given":"Morten H.","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Department of Intensive Care 4131 Copenhagen University Hospital  Rigshospitalet Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f8rgen","family":"Wiis","sequence":"additional","affiliation":[{"name":"Department of Intensive Care 4131 Copenhagen University Hospital  Rigshospitalet Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.4185.427"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0801327"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-015-1204-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-016-1314-5"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TA.0000130761.78627.10"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-003-1800-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.9774"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2007.06.037"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1R215"},{"key":"e_1_2_6_11_1","first-page":"CD008566","article-title":"Continuous renal replacement therapy (CRRT) for rhabdomyolysis","volume":"6","author":"Zeng X","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs040"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000000118"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.09.012"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.04.026"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198668030-00015"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199408000-00011"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-200X.2001.01469.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0922-y"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199704000-00010"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199703000-00015"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1988.00380070059015"},{"key":"e_1_2_6_24_1","first-page":"CD000567","article-title":"Colloids versus crystalloids for fluid resuscitation in critically ill patients","volume":"2","author":"Perel P","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.12334"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1711584"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1711586"},{"issue":"1","key":"e_1_2_6_28_1","first-page":"35","article-title":"Acute renal failure in earthquake victims in Iran: epidemiology and management","volume":"87","author":"Atef MR","year":"1994","journal-title":"Q J Med"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38902.605347.7C"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2009.06228.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000129336.09976.73"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-9572(84)90065-0"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1979.03630440059020"},{"issue":"4","key":"e_1_2_6_34_1","first-page":"305","article-title":"Crush syndrome: experience from the Lebanon War, 1982","volume":"20","author":"Michaelson M","year":"1984","journal-title":"Isr J Med Sci"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1984.00350140077012"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.3109\/08860229709026290"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/08860220701460095"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085029"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002267"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1710933"},{"key":"e_1_2_6_41_1","first-page":"CD006616","article-title":"N\u2010acetylcysteine for sepsis and systemic inflammatory response in adults","volume":"9","author":"Szakmany T","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc11316"},{"key":"e_1_2_6_43_1","first-page":"14","article-title":"The treatment effect of continuous venovenous hemofiltration on crush syndrome","volume":"25","author":"Dong W","year":"2005","journal-title":"Lin Chuang Yi Xue [Clin Med]"},{"issue":"85","key":"e_1_2_6_44_1","article-title":"The efficacy of CAVHD for crush syndrome","volume":"31","author":"Wang Z","year":"2008","journal-title":"Hei Long Jiang Yi Yao Ke Xue [Heilongjiang Med Pharm]"},{"key":"e_1_2_6_45_1","first-page":"307","article-title":"The efficacy of CVVH for acute kidney injury induced by rhabdomyolysis","volume":"29","author":"Zeng L","year":"2008","journal-title":"Si Chuan Yi Xue [Sichuan Med J]"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2017.05.002"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc11458"},{"key":"e_1_2_6_48_1","first-page":"CD010613","article-title":"Intensity of continuous renal replacement therapy for acute kidney injury","volume":"10","author":"Fayad AI","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"e_1_2_6_49_1","first-page":"595","article-title":"High\u2010volume hemofiltration in critically ill patients: a systematic review and meta\u2010analysis","volume":"80","author":"Lehner GF","year":"2014","journal-title":"Minerva Anestesiol"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f457"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs375"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2010.02.018"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4750-z"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4605-z"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4573-3"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1136\/emj.2006.043265"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.12429"},{"key":"e_1_2_6_58_1","first-page":"CD000567","article-title":"Colloids versus crystalloids for fluid resuscitation in critically ill people","volume":"8","author":"Lewis SR","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105387"},{"issue":"5","key":"e_1_2_6_60_1","first-page":"619","article-title":"Studies of mechanisms and protective maneuvers in myoglobinuric acute renal injury","volume":"60","author":"Zager RA","year":"1989","journal-title":"Lab Invest"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.48.31731"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annfar.2008.03.018"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.11.036"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01707664"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2007.01289.x"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2005.00577.x"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.17924"},{"key":"e_1_2_6_68_1","article-title":"European trial of free light chain removal by extended haemodialysis in cast nephropathy (EuLITE); survival and renal outcomes","volume":"27","author":"Hutchison CA","year":"2016","journal-title":"J Am Soc Nephrol"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.13308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.13308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aas.13308","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.13308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T14:48:42Z","timestamp":1694357322000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.13308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,15]]},"references-count":67,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/aas.13308"],"URL":"https:\/\/doi.org\/10.1111\/aas.13308","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,15]]},"assertion":[{"value":"2018-10-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}