{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:31:26Z","timestamp":1790857886345,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this quality assurance study was to determine the proportion of patients with residual block (train\u2010of\u2010four (TOF) ratio &lt;0.9) upon conclusion of surgery after a bolus of cisatracurium 0.1\u00a0mg\/kg. It was considered good quality if less than 10% of the study population had residual block upon conclusion of surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 40 patients \u22643\u00a0years of age scheduled for cleft lip and palate repair were consecutively enrolled. They received general anaesthesia with either sevoflurane and fentanyl (n\u00a0=\u00a020) or propofol and remifentanil (n\u00a0=\u00a020). TOF stimulation using acceleromyography was applied on the tibial nerve. Cisatracurium 0.1\u00a0mg\/kg was administered to facilitate tracheal intubation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three patients (8%; 95% CI: 1.7\u201021) had a TOF ratio &lt;0.9 at conclusion of surgery, all three receiving sevoflurane. In the sevoflurane group, this corresponded to 16% (95% CI: 3.3\u201040) of the patients. Mean duration of action of cisatracurium 0.1\u00a0mg\/kg was 119\u00a0minutes (SD 40) with sevoflurane and 73\u00a0minutes (SD 29) during total intravenous anaesthesia (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). Onset time of cisatracurium 0.1\u00a0mg\/kg was 166\u00a0seconds (SD 37) with sevoflurane and 199\u00a0seconds (SD 60) during total intravenous anaesthesia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found that 8% of the children had residual neuromuscular blockade (TOF ratio &lt;0.9) after administration of a single bolus of cisatracurium 0.1\u00a0mg\/kg but we cannot exclude that the true proportion is around 20%.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13495","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T18:06:14Z","timestamp":1572026774000},"page":"168-172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Incidence of residual neuromuscular blockade in children below 3 years after a single bolus of cisatracurium 0.1\u00a0mg\/kg: A quality assurance study"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5165-2725","authenticated-orcid":false,"given":"Matias","family":"Vested","sequence":"first","affiliation":[{"name":"Department of Anaesthesia Centre of Head and Orthopedics, Rigshospitalet University of Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Tarpgaard","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Centre of Head and Orthopedics, Rigshospitalet University of Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Eriksen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Centre of Head and Orthopedics, Rigshospitalet University of Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars S.","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Centre of Head and 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