{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:54:47Z","timestamp":1787792087590,"version":"build-2784847793"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T00:00:00Z","timestamp":1580428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The deceased organ donation rate in Iceland has been low compared with other Western countries. The aim of this study was to explore the potential for organ donation after brain death in Iceland.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Observational cohort study of patients with catastrophic brain injury who died in intensive care units (ICUs) at hospitals in Iceland in 2003\u20102016. Medical records were retrospectively reviewed to identify potential donors (PDs), using the WHO Critical Pathway for Deceased Donation. Trends in annual incidence of PDs, conversion to actual donors, and family refusals were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 1537 patients who died in the ICU, 125 (8.1%) were identified as PDs. Of 103 PDs who were declared brain dead, consent for organ donation was pursued in 84 cases and granted in 63. Fifty\u2010six became actual donors. The annual donation rate averaged 13 per million population (pmp), but rose abruptly in the final 2\u00a0years to 36 and 27 pmp, respectively. This was paralleled by an increase in annual incidence of PDs from an average of 28 pmp to 54 and 42 pmp, respectively. The donor conversion rate increased during the study period (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.026). Twenty\u2010three PDs (18%) were not pursued without an apparent reason.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The donation rate increased markedly in the last 2\u00a0years of the study period after remaining low for more than a decade. This change can largely be explained by a high incidence of PDs and a low family refusal rate. Missed donation opportunities suggest a potential to maintain a high donation rate in the future.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13551","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T08:39:58Z","timestamp":1579250398000},"page":"663-669","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The potential for organ donation in Iceland: A nationwide study of deaths in intensive care units"],"prefix":"10.1111","volume":"64","author":[{"given":"Thordur P.","family":"Palsson","sequence":"first","affiliation":[{"name":"Faculty of Medicine School of Health Sciences University of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristinn","family":"Sigvaldason","sequence":"additional","affiliation":[{"name":"Division of Anesthesia and Intensive Care Medicine Landspitali\u2014The National University Hospital of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thora E.","family":"Kristjansdottir","sequence":"additional","affiliation":[{"name":"Division of Anesthesia and Intensive Care Medicine Landspitali\u2014The National University Hospital of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thordur","family":"Thorkelsson","sequence":"additional","affiliation":[{"name":"Division of Neonatal Intensive Care Children\u2019s Medical Center Landspitali\u2014The National University Hospital of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asbjorn T.","family":"Blondal","sequence":"additional","affiliation":[{"name":"Division of Anesthesia and Intensive Care Akureyri Hospital Akureyri Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0726-4378","authenticated-orcid":false,"given":"Sigurbergur","family":"Karason","sequence":"additional","affiliation":[{"name":"Faculty of Medicine School of Health Sciences University of Iceland Reykjavik Iceland"},{"name":"Division of Anesthesia and Intensive Care Medicine Landspitali\u2014The National University Hospital of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6763-1702","authenticated-orcid":false,"given":"Runolfur","family":"Palsson","sequence":"additional","affiliation":[{"name":"Faculty of Medicine School of Health Sciences University of Iceland Reykjavik Iceland"},{"name":"Internal Medicine Services Landspitali\u2014The National University Hospital of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-014-2639-3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1507080"},{"key":"e_1_2_8_4_1","first-page":"70","article-title":"International figures on donation and transplantation","volume":"2017","author":"Matesanz R","year":"2016","journal-title":"Newsletter Transplant"},{"key":"e_1_2_8_5_1","first-page":"417","article-title":"L\u00edff\u00e6ragjafir \u00e1 \u00cdslandi 1992\u20132002 [Organ donations in Iceland 1992\u20132002]","volume":"91","author":"K\u00e1rason S","year":"2005","journal-title":"Laeknabladid [Icelandic Med J]"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2011.01243.x"},{"key":"e_1_2_8_7_1","unstructured":"Scandiatransplant.Scandiatransplant figures. Available from:http:\/\/www.scandiatransplant.org\/data\/scandiatransplant-figures. Accessed March 3 2019."},{"key":"e_1_2_8_8_1","unstructured":"Frumvarp til laga um breytingu \u00e1 l\u00f6gum um brottnam l\u00edff\u00e6ra nr. 16\/1991 (\u00e6tla\u00f0 sam\u00feykki) [Change in Organ Removal Law No. 16\/1991 (presumed consent) Bill].Reykjavik:Althingi [Icelandic Parliament];2014."},{"key":"e_1_2_8_9_1","unstructured":"Var\u00f0 andlit l\u00edff\u00e6ragjafa [Became the face of organ donors] Kastlj\u00f3s [News programme].Reykjavik:RUV [The Icelandic National Broadcasting Service];2014."},{"key":"e_1_2_8_10_1","unstructured":"Sigur\u00fe\u00f3rsd\u00f3ttirSK.36 pr\u00f3sent fleiri l\u00edff\u00e6ragjafar eftir s\u00f6gu Dagn\u00fdjar [Thirty-six percent increase in registered organ donors following Dagny\u2018s story]. Visir [online newspaper].Reykjavik:2015."},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2006.00413.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31823411bb"},{"key":"e_1_2_8_13_1","first-page":"w14045","article-title":"Swiss monitoring of potential organ donors (SwissPOD): a prospective 12\u2010month cohort study of all adult ICU deaths in Switzerland","volume":"144","author":"Weiss J","year":"2014","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.12831"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-010231"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa021271"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38804.658183.55"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31826dde40"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.12853"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000079317.75840.0F"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04138.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4549-3"},{"key":"e_1_2_8_23_1","unstructured":"Accord. EU Joint Action: Achieving Comprehensive Coordination in Organ Donation throughout the European Union. Work Package 5 \u2013 Increasing the collaboration between donor transplant coordinators and intensive care professionals.http:\/\/www.accord-ja.eu\/sites\/default\/files\/download_documents\/ACCORD_WP_5_ICU_%26_DTC_Collaboration_FINAL_REPORT.pdf. Accessed February 10 2019."},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001701"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc1542"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc12553"},{"key":"e_1_2_8_27_1","first-page":"333","article-title":"T\u00f3lf gj\u00f6rg\u00e6slur\u00fam \u00e1 Landsp\u00edtala \u2013 dugar \u00fea\u00f0 til? [Is there lack of ICU beds in Iceland?]","volume":"104","author":"Karason S","year":"2018","journal-title":"Laeknabladid [Icelandic Med J]"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2627-8"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.13551","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.13551","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aas.13551","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.13551","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T08:26:51Z","timestamp":1694075211000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.13551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,31]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1111\/aas.13551"],"URL":"https:\/\/doi.org\/10.1111\/aas.13551","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,31]]},"assertion":[{"value":"2019-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}