{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:28:10Z","timestamp":1777919290736,"version":"3.51.4"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T00:00:00Z","timestamp":1585872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671116"],"award-info":[{"award-number":["81671116"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>This study is to investigate if non\u2010intubated anaesthesia combined with paravertebral nerve block (PVNB) can enhance recovery in children undergoing video\u2010assisted thoracic surgery (VATS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A randomized controlled trial including 60 patients aged 3 to 8\u00a0years old who underwent elective VATS was performed. They were randomly assigned to receive non\u2010intubated anaesthesia combined with PVNB or general anaesthesia with tracheal intubation (1:1 ratio). The primary outcome was the length of postoperative in\u2010hospital stay. The secondary outcomes included emergence time, the incidence of emergence delirium, time to first feeding, time to first out\u2010of\u2010bed activity, pain score and in\u2010hospital complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The non\u2010intubated group had shorter postoperative in\u2010hospital stay than the control group (4\u00a0days [IQR, 4\u20106] vs 5\u00a0days [IQR, 5\u20108], 95% CI 0\u20102; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.013). When compared to the control group, the incidence of emergence delirium (odds ratio [OR] 3.39, 95% CI 1.01\u201011.41; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.043), emergence time, duration in the PACU, time to first eating food, first out\u2010of\u2010bed activity, pain score and consumption of sufentanil (at 6 and 12\u00a0hours after surgery) were decreased in the intervention group. In contrast, the incidence of airway complications was higher in the control than the intervention group (27.6% vs 6.9%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.037). There was no statistical significance in the occurrence of PONV, pneumothorax and other complications between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Non\u2010intubated anaesthesia combined with PVNB enhances recovery in paediatric patients for video\u2010assisted thoracic surgery although further multi\u2010centre study is needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13572","type":"journal-article","created":{"date-parts":[[2020,3,8]],"date-time":"2020-03-08T00:51:00Z","timestamp":1583628660000},"page":"810-818","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Combined non\u2010intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video\u2010assisted thoracic surgery"],"prefix":"10.1111","volume":"64","author":[{"given":"Wei","family":"Wei","sequence":"first","affiliation":[{"name":"Department of 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