{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:30:25Z","timestamp":1784305825430,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T00:00:00Z","timestamp":1592438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"publisher","award":["Regional research support"],"award-info":[{"award-number":["Regional research support"]}],"id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Sepsis is a common indication for admission to the intensive care unit (ICU). Since definitions vary across studies, comparisons of prevalence and outcomes have been challenging. We aimed to compare sepsis according to ICU discharge codes with sepsis according to Sepsis\u20103 criteria and to investigate the epidemiology of sepsis in the ICU. We hypothesized that sepsis using discharge codes is underreported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adult ICU admissions to four ICUs in Sweden between 2015 and 2017 were screened for sepsis according to the Sepsis\u20103 criteria. Medical records were reviewed and data extracted from the Swedish Intensive Care Registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 5990 adult ICU patients, 28% fulfilled the Sepsis\u20103 criteria on admission, but only 31% of them had sepsis as the registered main diagnosis at ICU discharge. Of the 1654 Sepsis\u20103 patients, 38% met the septic shock criteria. The Sepsis\u20103 in\u2010hospital mortality was 26% compared to 33% in patients with septic shock. The incidence rate for ICU\u2010treated sepsis was 81 cases per 100\u00a0000 person\u2010years. One in four had a positive blood culture, and 44% were culture negative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This large Swedish multicentre study showed that 28% of adult ICU patients fulfilled the Sepsis\u20103 criteria, but only one third of them had sepsis according to ICU discharge codes. We could confirm our hypothesis, that sepsis is severely underreported in Swedish ICUs, and we conclude that discharge codes should not be used for quality control or research purposes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13647","type":"journal-article","created":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T09:15:02Z","timestamp":1590657302000},"page":"1167-1176","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Sepsis is underreported in Swedish intensive care units: A retrospective observational multicentre study"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4080-396X","authenticated-orcid":false,"given":"Maria","family":"Lengquist","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Anaesthesiology and Intensive Care Lund University Lund Sweden"},{"name":"Sk\u00e5ne University Hospital Intensive and Perioperative Care Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9295-6944","authenticated-orcid":false,"given":"Oscar H. M.","family":"Lundberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Anaesthesiology and Intensive Care Lund University Lund Sweden"},{"name":"Sk\u00e5ne University Hospital Intensive and Perioperative Care Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8754-899X","authenticated-orcid":false,"given":"Martin","family":"Sp\u00e5ngfors","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Anaesthesiology and Intensive Care Lund University Lund Sweden"},{"name":"Department of Anaesthesia and Intensive Care Kristianstad Hospital Kristianstad Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1074-9512","authenticated-orcid":false,"given":"Martin","family":"Annborn","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Anaesthesiology and Intensive Care Lund University Lund 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Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0155-4828","authenticated-orcid":false,"given":"Attila","family":"Frigyesi","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Anaesthesiology and Intensive Care Lund University Lund Sweden"},{"name":"Sk\u00e5ne University Hospital Intensive and Perioperative Care Lund 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