{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:22:34Z","timestamp":1771464154497,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:00:00Z","timestamp":1595980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81401089"],"award-info":[{"award-number":["81401089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81730031"],"award-info":[{"award-number":["81730031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In the monitored anesthesia care (MAC) setting for awake craniotomy (AC), maintaining airway patency in sedated patients remains challenging. This randomized controlled trial aimed to compare the validity of the below\u2010epiglottis transnasal tube insertion (the tip of the tube placed between the epiglottis and vocal cords) and the nasopharyngeal airway (simulated by the above\u2010epiglottis transnasal tube with the tip of the tube placed between the epiglottis and the free edge of the soft palate) with respect to maintaining upper airway patency for moderately sedated patients undergoing AC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty patients scheduled for elective AC were randomized to receive below\u2010epiglottis (n\u00a0=\u00a030) or above\u2010epiglottis (n\u00a0=\u00a030) transnasal tube insertion before surgery. Moderate sedation was maintained in the pre\u2010 and post\u2010awake phases. The primary outcome was the upper airway obstruction (UAO) remission rate (relieved obstructions after tube insertion\/the total number of obstructions before tube insertion).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The UAO remission rate was higher in the below\u2010epiglottis group [100% (12\/12) vs 45% (5\/11); <jats:italic>P<\/jats:italic>\u00a0=\u00a0.005]. The tidal volume values monitored through the tube were greater in the below\u2010epiglottis group during the pre\u2010awake phase (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). End\u2010tidal carbon dioxide (EtCO<jats:sub>2<\/jats:sub>) monitored through the tube was higher in the below\u2010epiglottis group at bone flap removal (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). During the awake phase, patients' ability to speak was not impeded. No patient had serious complications related to the tube.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The below\u2010epiglottis tube insertion is a more effective method to maintain upper airway patency than the nasopharyngeal airway for moderately sedated patients undergoing AC.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13667","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T22:00:04Z","timestamp":1594677604000},"page":"1414-1421","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparing two airway management strategies for moderately sedated patients undergoing awake craniotomy: A single\u2010blinded randomized controlled trial"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1484-3039","authenticated-orcid":false,"given":"Meng","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Huashan Hospital of Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng\u2010Yun","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Huashan Hospital of Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7778-2368","authenticated-orcid":false,"given":"Yi\u2010Heng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Huashan Hospital of Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Bing","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Huashan Hospital of Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin\u2010Song","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Huashan Hospital of Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2554-6611","authenticated-orcid":false,"given":"Ying\u2010Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Huashan Hospital of Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/JNS-07\/07\/0001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANA.0b013e318290c230"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aew024"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-017-0840-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0265021508003633"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000181287.86811.5C"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.23736\/S0375-9393.17.11873-0","article-title":"Propofol\u2010dexmedetomidine versus propofol\u2010remifentanil conscious sedation for awake craniotomy during epilepsy surgery","volume":"83","author":"Elbakry AE","year":"2017","journal-title":"Minerva Anestesiol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeg126"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1993.tb07119.x"},{"key":"e_1_2_7_11_1","first-page":"244","article-title":"Validity and reliability of the observer's assessment of alertness\/sedation scale: study with intravenous midazolam","volume":"10","author":"Chernik DA","year":"1990","journal-title":"J Clin Psychopharmacol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0199120"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANA.0000000000000032"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/ANA.0000000000000378"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199602000-00004"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199906000-00018"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.5.667"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002430"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13616"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2017.01.025"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeg037"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002883"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001072"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000000255"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1265896"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2018.09.029"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2016.10.007"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2012.09.031"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen240"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faas.13667","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.13667","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aas.13667","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aas.13667","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T01:21:53Z","timestamp":1693876913000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aas.13667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,29]]},"references-count":28,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/aas.13667"],"URL":"https:\/\/doi.org\/10.1111\/aas.13667","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,29]]},"assertion":[{"value":"2020-03-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}