{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T02:33:23Z","timestamp":1771641203144,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T00:00:00Z","timestamp":1628467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The optimal pain therapy for children undergoing tonsillotomy remains unknown. Our aim was to evaluate a standard pain therapy including the alternating application of ibuprofen and paracetamol.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pain intensity of 81 in\u2010patients after tonsillotomy aged 2\u201312\u00a0years was evaluated three times daily (mean observation 3.85\u00a0days) using the Children's and Infants\u2019 Postoperative Pain Scale (CHIPPS) in children &lt;5\u00a0years, or with the Faces Pain Scale\u2010Revised (FPS\u2010R) in older children. Parents completed the Parents\u2019 Postoperative Pain Measure (PPPM\u2010D) in addition. Exceeding the cut\u2010off value in one of the scores implied the indication for an opioid rescue medication (RM). Endpoints were number of children with indication for the RM, course of pain, concordance between pain scales, and adverse events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 45.7% of children needed the RM either in the recovery room or on the ward. The rate of children having an indication for RM on the ward was 30.9%. The highest proportion of affected children was identified on the day of surgery (32.1%). Most indications were detected with the PPPM\u2010D only. A comparison with an earlier study showed less affected children compared to ibuprofen monotherapy on the day of surgery and the first postoperative day. Eleven children (13.6%) developed fever.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although our pain therapy concept was effective from postoperative day 1 onwards, it needs improvement for the day of surgery. The overall concordance between the PPPM\u2010D and CHIPPS or FPS\u2010R was low. Fever might be a confounder for the pain intensity measurement with the PPPM\u2010D.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.13959","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T18:16:40Z","timestamp":1627323400000},"page":"1374-1380","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pain in children undergoing tonsillotomy with alternating ibuprofen and paracetamol \u2010 a prospective observational study"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3045-3823","authenticated-orcid":false,"given":"Philipp","family":"Gude","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Ruhr\u2010University Bochum St. Josef\u2010 and St. Elisabeth\u2010Hospital Bochum Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niclas","family":"Geldermann","sequence":"additional","affiliation":[{"name":"Department 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