{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T12:02:09Z","timestamp":1786708929899,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mortality due to acute hypoxemic respiratory failure (AHRF) in patients with coronavirus disease\u201019 (COVID\u201019) differs across units, regions, and countries. These variations may be attributed to several factors, including comorbidities, acute physiological derangement, disease severity, treatment, ethnicity, healthcare system strain, and socioeconomic status. This study aimed to explore the features of patient characteristics, clinical management, and staffing that may be related to mortality among three intensive care units (ICUs) within the same hospital system in South Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed ICU patients with COVID\u201019 and AHRF in Region J\u00f6nk\u00f6ping County, Sweden. The primary outcome was the 90\u2010day mortality rate. We used univariate and multivariable logistic regression analyses to investigate the relationship of predictors with outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between March 15, 2020, and May 31, 2021, 331 patients with AHRF and COVID\u201019 were admitted to the three ICUs. There were differences in disease severity, treatments, process\u2010related factors, and socioeconomic factors between the units. These factors were related to 90\u2010day mortality. After multivariable adjustment, age, severity of acute respiratory distress syndrome, and the number of nurses per ICU\u2010bed independently predicted 90\u2010day mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Age, disease severity, and nurse staffing, but not treatment or socioeconomic status, were independently associated with 90\u2010day mortality among critically ill patients with AHRF due to COVID\u201019. We also identified variations in care related processes, which may be a modifiable risk factor and warrants future investigation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.14232","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T06:14:55Z","timestamp":1678774495000},"page":"788-796","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Factors related to <scp>COVID<\/scp>\u201019 mortality among three <scp>Swedish<\/scp> intensive care units\u2014A retrospective study"],"prefix":"10.1111","volume":"67","author":[{"given":"Knut","family":"Taxbro","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Medicine Ryhov County Hospital  J\u00f6nk\u00f6ping Sweden"},{"name":"Department of Biomedical and Clinical Sciences Link\u00f6ping University  Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrik","family":"Hammarskj\u00f6ld","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Medicine Ryhov County Hospital  J\u00f6nk\u00f6ping Sweden"},{"name":"Department of Biomedical and Clinical Sciences Link\u00f6ping University  Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Clinical Sciences Link\u00f6ping University  Link\u00f6ping Sweden"},{"name":"Futurum, Academy of Health and Care Region J\u00f6nk\u00f6ping County  J\u00f6nk\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Persson","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Medicine V\u00e4rnamo Hospital  V\u00e4rnamo Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle S.","family":"Chew","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Clinical Sciences Link\u00f6ping University  Link\u00f6ping Sweden"},{"name":"Department of Anaesthesia and Intensive Care Medicine Link\u00f6ping University Hospital  Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola","family":"Sunnergren","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Region J\u00f6nk\u00f6ping County  J\u00f6nk\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"\u00c5rsrapport UF 2020\u20132021","author":"Swedish Intensive Care Registry","year":"2021"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202012-4547OC"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00634-6"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06150-y"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2521-4"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30368-4"},{"key":"e_1_2_9_8_1","unstructured":"The SAPS 3 Research Group.2021.Accessed June 02 2022.www.saps3.org."},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31819def97"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2016.05.022"},{"key":"e_1_2_9_11_1","volume-title":"SIR diagnostic criteria, [internet document]","author":"Swedish Intensive Care Registry","year":"2021"},{"key":"e_1_2_9_12_1","unstructured":"KDIGO Clinical Practice Guideline for Acute Kidney Injury [Internet document].2016Accessed February 02 2022.https:\/\/kdigo.org\/wp-content\/uploads\/2016\/10\/KDIGO\u20102012\u2010AKI\u2010Guideline\u2010English.pdf"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00439-6"},{"key":"e_1_2_9_14_1","volume-title":"Intensive Care Guidelines, [Internet Document]","author":"Svensk F\u00f6rening f\u00f6r Anestesi och Intensivv\u00e5rd","year":"2015"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-022-01011-x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1001025"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iccn.2021.103110"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62631-8"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00768-6"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1201918"},{"key":"e_1_2_9_21_1","article-title":"COVID\u201019 mortality in ICUs associated with critical care staffing. 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